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Thus, the present study investigated the association of CM with lGI in women with EDs. Twenty\u2010six women with anorexia nervosa (AN) and 24 with bulimia nervosa (BN) underwent a 3T MRI scan. All participants filled in the Childhood Trauma Questionnaire. All neuroimaging data were processed by FreeSurfer. LGI maps underwent a general linear model to evaluate differences between groups with or without CM. People with AN and BN were merged together. Based on the Childhood Trauma Questionnaire cutoff scores, 24 participants were identified as maltreated and 26 as non\u2010maltreated. Maltreated people with EDs showed a significantly lower lGI in the left middle temporal gyrus compared with non\u2010maltreated people, whereas no differences emerged in the right hemisphere between groups. The present study showed that in people with EDs, CM is associated with reduced cortical folding in the left middle temporal gyrus, an area that could be involved in ED psychopathology. This finding corroborates the hypothesis of a \u2018maltreated ecophenotype\u2019, which argues that CM may allow to biologically, other than clinically, distinguish individuals with the same psychiatric disorder.<\/jats:p>","DOI":"10.1111\/ejn.16076","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T23:04:30Z","timestamp":1687907070000},"page":"2868-2873","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association between childhood maltreatment and cortical folding in women with eating disorders"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0358-8594","authenticated-orcid":false,"given":"Giammarco","family":"Cascino","sequence":"first","affiliation":[{"name":"Department of Medicine, Surgery and Dentistry \u2018Scuola Medica Salernitana\u2019, Section of Neurosciences University of Salerno  Salerno 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