{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T01:23:04Z","timestamp":1783387384910,"version":"3.54.6"},"reference-count":69,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,9,19]],"date-time":"2023-09-19T00:00:00Z","timestamp":1695081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2020\u201002140"],"award-info":[{"award-number":["2020\u201002140"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Most individuals experience their dominant arm as being more dexterous than the non\u2010dominant arm, but the neural mechanisms underlying this asymmetry in motor behaviour are unclear. Using a delayed\u2010reach task, we have recently demonstrated strong goal\u2010directed tuning of stretch reflex gains in the dominant upper limb of human participants. Here, we used an equivalent experimental paradigm to address the neural mechanisms that underlie the preparation for reaching movements with the non\u2010dominant upper limb. There were consistent effects of load, preparatory delay duration and target direction on the long latency stretch reflex. However, by comparing stretch reflex responses in the non\u2010dominant arm with those previously documented in the dominant arm, we demonstrate that goal\u2010directed tuning of short and long latency stretch reflexes is markedly weaker in the non\u2010dominant limb. The results indicate that the motor performance asymmetries across the two upper limbs are partly due to the more sophisticated control of reflexive stiffness in the dominant limb, likely facilitated by the superior goal\u2010directed control of muscle spindle receptors. Our findings therefore suggest that fusimotor control may play a role in determining performance of complex motor behaviours and support existing proposals that the dominant arm is better supplied than the non\u2010dominant arm for executing more complex tasks, such as trajectory control.<\/jats:p>","DOI":"10.1111\/ejn.16148","type":"journal-article","created":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T02:24:50Z","timestamp":1695176690000},"page":"3981-4001","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Goal\u2010directed modulation of stretch reflex gains is reduced in the non\u2010dominant upper limb"],"prefix":"10.1111","volume":"58","author":[{"given":"Frida","family":"Torell","sequence":"first","affiliation":[{"name":"Physiology Section, Department of Integrative Medical Biology Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sae","family":"Franklin","sequence":"additional","affiliation":[{"name":"Neuromuscular Diagnostics, Department of Sport and Health Sciences Technical University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Franklin","sequence":"additional","affiliation":[{"name":"Neuromuscular Diagnostics, Department of Sport and Health Sciences Technical University of Munich  Munich Germany"},{"name":"Munich Institute of Robotics and Machine Intelligence (MIRMI) Technical University of Munich  Munich Germany"},{"name":"Munich Data Science Institute (MDSI) Technical University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Dimitriou","sequence":"additional","affiliation":[{"name":"Physiology Section, Department of Integrative Medical Biology Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1998.80.3.1373"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4275-11.2012"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1983.49.1.16"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14640747908400755"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00189.2003"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-022-04576-9"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0317167100045534"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1010192"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0317167100032947"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.09.015"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0896-6273(04)00267-3"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1976.39.5.925"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00536.2020"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2004.01.014"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2611-14.2014"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2016.02.030"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1037\/bne0000241"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.78091"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00250264"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3099-08.2008"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0968-07.2007"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-003-1540-3"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1982.tb06983.x"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/pl00005692"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2007.10.006"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.90259.2008"},{"key":"e_1_2_11_28_1","volume-title":"Signal detection theory and psychophysics","author":"Green D. 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