{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T20:54:46Z","timestamp":1792270486784,"version":"4.4.0"},"reference-count":120,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T00:00:00Z","timestamp":1701820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>While colloquially recognized for its role in pleasure, reward, and affect, dopamine is also necessary for proficient action control. Many motor studies focus on dopaminergic transmission along the nigrostriatal pathway, using Parkinson's disease as a model of a dorsal striatal lesion. Less attention to the mesolimbic pathway and its role in motor control has led to an important question related to the limbic\u2013motor network. Indeed, secondary targets of the mesolimbic pathway include the hippocampus and amygdala, and these are linked to the motor cortex through the substantia nigra and thalamus. The modulatory impact of dopamine in the hippocampus and amygdala in humans is a focus of current investigations. This review explores dopaminergic activity in the mesial temporal lobe by summarizing dopaminergic networks and transmission in these regions and examining their role in behaviour and disease.<\/jats:p>","DOI":"10.1111\/ejn.16209","type":"journal-article","created":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T16:40:21Z","timestamp":1701967221000},"page":"1141-1152","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Mesial temporal dopamine: From biology to behaviour"],"prefix":"10.1111","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6877-4761","authenticated-orcid":false,"given":"Leah G.","family":"Mann","sequence":"first","affiliation":[{"name":"Vanderbilt Brain Institute Vanderbilt University  Nashville Tennessee USA"},{"name":"Department of Neurology Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel O.","family":"Claassen","sequence":"additional","affiliation":[{"name":"Department of Neurology Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2097-04.2005"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073858410395147"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2007.07.014"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1063(1999)9:1<1::AID-HIPO1>3.0.CO;2-T"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2008.07.004"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-6147(90)90249-8"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.49995"},{"key":"e_1_2_10_9_1","first-page":"253","volume-title":"Fundamentals of cognitive neuroscience","author":"Baars B. J.","year":"2013"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2013.00152"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.110.002642"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001171"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awg034"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02157069"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2007.03.006"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cphy.cp010403"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhp289"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02156938"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145711000812"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.06-11-03177.1986"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2014.00047"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70118-2"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10444"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-018-2109-y"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.127.3296.471"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2014.00053"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.07-05-01352.1987"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70068-7"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(92)90099-n"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2004.09.009"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24323"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.49.6.1570"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-03-01714.1995"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(88)90212-0"},{"key":"e_1_2_10_35_1","first-page":"1","article-title":"Evidence for the existence of monoamine\u2010containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons","volume":"232","author":"Dahlstroem A.","year":"1964","journal-title":"Acta Physiologica Scandinavica. Supplementum"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2010.12.017"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.2165\/11586390-000000000-00000"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-018-2800-7"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhaa354"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb09280.x"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901800310"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.1998.00133.x"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1983.63.3.844"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/hipo.22044"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(94)90288-7"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0278-5846(96)00157-1"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.21921"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2011.05.011"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(88)90353-8"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4530(81)90044-5"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/23.3.471"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/2727602"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf251"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-30382-6_7"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10420"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-015-3897-y"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2013.04.007"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.14927"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10115"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-03-01137.2002"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-02-00676.2001"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.30.12.1326"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(93)90199-u"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.1.13"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1038\/277093a0"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1616515114"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2003.02716.x"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-018-0632-3"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0805722105"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/1098-1063(2000)10:4<420::AID-HIPO8>3.0.CO;2-5"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1965.tb01744.x"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902890104"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073858416679936"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24935"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2005.05.002"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2019.01.001"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300963"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2011.05.001"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901890406"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2244-05.2006"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.09.023"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-019-0506-0"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0968-21.2021"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn_a_02048"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(91)90233-e"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0896-6273(00)80041-0"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbu084"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2017.05.005"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.1994.27"},{"issue":"4","key":"e_1_2_10_90_1","first-page":"231","article-title":"Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in rat brain","volume":"5","author":"Meador\u2010Woodruff J. H.","year":"1991","journal-title":"Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.40.070171.002341"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14727"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199905)45:5<601::AID-ANA8>3.0.CO;2-0"},{"key":"e_1_2_10_94_1","volume-title":"StatPearls","author":"Patel A.","year":"2022"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pscychresns.2011.06.014"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A4169"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2396(199602)22:2<93::AID-SYN1>3.0.CO;2-C"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2014.03.013"},{"key":"e_1_2_10_99_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.117.013995"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(90)90439-b"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(59)90652-3"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(80)90314-6"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2000.tb06715.x"},{"key":"e_1_2_10_104_1","first-page":"1189","volume-title":"Radioactive isotopes in physiology diagnostics and therapy","author":"Schayer R. W.","year":"1961"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(20000501)420:2<211::AID-CNE5>3.0.CO;2-3"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1002\/syn.890110208"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2005.11.033"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.6486-11.2012"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(82)90145-9"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature19325"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1796-19.2020"},{"issue":"1","key":"e_1_2_10_112_1","first-page":"427","article-title":"[3H]nisoxetine: A radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding","volume":"260","author":"Tejani\u2010Butt S. M.","year":"1992","journal-title":"The Journal of Pharmacology and Experimental Therapeutics"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2018.05.021"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-201x.1971.tb10998.x"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2005.075341"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2013.07.005"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1714082115"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12512"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.5.1859"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1406"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2017.00247"}],"updated-by":[{"DOI":"10.1111\/ejn.16339","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000}}],"container-title":["European Journal of Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejn.16209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T11:02:53Z","timestamp":1711018973000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ejn.16209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,6]]},"references-count":120,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1111\/ejn.16209"],"URL":"https:\/\/doi.org\/10.1111\/ejn.16209","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/EJN.16209\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16209\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16209\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16209\/v2\/response1","asserted-by":"object"}]},"ISSN":["0953-816X","1460-9568"],"issn-type":[{"value":"0953-816X","type":"print"},{"value":"1460-9568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,6]]},"assertion":[{"value":"2023-08-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}