{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:43:53Z","timestamp":1772160233857,"version":"3.50.1"},"reference-count":54,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T00:00:00Z","timestamp":1715212800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100018510","name":"Texas Woman's University","doi-asserted-by":"publisher","award":["Student Research Grant"],"award-info":[{"award-number":["Student Research Grant"]}],"id":[{"id":"10.13039\/100018510","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Both the primary motor cortex (M1) and the cerebellum are crucial for postural stability and deemed as potential targets for non\u2010invasive brain stimulation (NIBS) to enhance balance performance. However, the optimal target remains unknown. The purpose of this study was to compare the role of M1 and the cerebellum in modulating balance performance in young healthy adults using facilitatory 5\u00a0Hz repetitive transcranial magnetic stimulation (rTMS). Twenty\u2010one healthy young adults (mean age\u2009=\u200927.95\u2009\u00b1\u00a01.15\u2009years) received a single session of 5\u00a0Hz rTMS on M1 and the cerebellum in a cross\u2010over order with a 7\u2010day washout period between the two sessions. Three balance assessments were performed on the Biodex Balance system SD: Limits of Stability (LOS), modified Clinical Test of Sensory Interaction on Balance (mCTSIB), and Balance Error Scoring System (BESS). No significant effect of rTMS was found on the LOS. The effect of rTMS on the mCTSIB was mediated by stimulation target, proprioception, and vision (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.003, \u03b7\n                    <jats:sub>p<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090.37). Cerebellar rTMS improved the mCTSIB sway index under eyes closed\u2010foam surface condition (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.02), whereas M1 rTMS did not result in improvement on the mCTSIB. The effect of rTMS on the BESS was mediated by stimulation target, posture, and proprioception (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u2009.049, \u03b7\n                    <jats:sub>p<\/jats:sub>\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090.14). Cerebellar rTMS enhanced reactive balance performance during most sensory deprived conditions.\n                  <\/jats:p>","DOI":"10.1111\/ejn.16386","type":"journal-article","created":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T03:43:20Z","timestamp":1715226200000},"page":"3984-3994","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effects of rTMS to primary motor cortex and cerebellum on balance control in healthy adults"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0392-5836","authenticated-orcid":false,"given":"Vyoma","family":"Parikh","sequence":"first","affiliation":[{"name":"School of Physical Therapy Texas Woman's University  United States"},{"name":"School of Medicine Emory University  United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann","family":"Medley","sequence":"additional","affiliation":[{"name":"School of Physical Therapy Texas Woman's University  United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9460-9869","authenticated-orcid":false,"given":"Hui\u2010Ting","family":"Goh","sequence":"additional","affiliation":[{"name":"School of Physical Therapy Texas Woman's University  United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,9]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucli.2020.01.006"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/brain.2020.0872"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1941738111403122"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-13-102"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1682\/jrrd.2003.09.0140"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/73.6.346"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000002163"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0170331"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2012.00116"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/08990220.2019.1624517"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e3181c1f7c5"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3233\/NRE-141077"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/EJN.13731"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12311-017-0863-8"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/NPT.0000000000000064"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2016.00325"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/14734220701216440"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-007-0657-0"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2014.11.048"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.2478\/v10078-008-0003-0"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2016.03.018"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rehab.2015.05.006"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2011.11.005"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.04.070"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/s22197527"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci12070929"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.26582\/k.55.2.4"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1589\/jpts.24.1215"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEP.0b013e31812574a9"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0749-0690(18)30193-9"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1371\/JOURNAL.PONE.0107731"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-46.6.600"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.CLINPH.2016.11.029"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1191\/0269215500cr342oa"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2017.09.118"},{"key":"e_1_2_12_37_1","first-page":"189","volume-title":"Neuroscience","year":"2011"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.3810\/psm.2014.09.2073"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.3389\/FNSYS.2014.00205"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2009.08.016"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2015.02.001"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0749-0690(02)00002-2"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-00509-w"},{"issue":"6","key":"e_1_2_12_44_1","first-page":"395","article-title":"Postural sway biofeedback: Its effect on reestablishing stance stability in hemiplegic patients","volume":"69","author":"Shumway\u2010Cook A.","year":"1988","journal-title":"Archives of Physical Medicine and Rehabilitation"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2017.02.005"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0163598"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-09712-8"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.14802\/jmd.16062"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/823285"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0189876"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2018.11.026"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.26603\/001c.18713"},{"key":"e_1_2_12_53_1","first-page":"134","volume-title":"Encyclopedia of neuroscience","author":"Woollacott M.","year":"2009"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.5812\/ircmj.90337"},{"key":"e_1_2_12_55_1","unstructured":"Yoo H. &Mihaila D. M.(2022).Neuroanatomy Vestibular Pathways. InStatPearls.http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32491312"}],"container-title":["European Journal of Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejn.16386","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T04:23:07Z","timestamp":1721362987000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ejn.16386"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,9]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/ejn.16386"],"URL":"https:\/\/doi.org\/10.1111\/ejn.16386","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/EJN.16386\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16386\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16386\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16386\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16386\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16386\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16386\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.16386\/v2\/review1","asserted-by":"object"}]},"ISSN":["0953-816X","1460-9568"],"issn-type":[{"value":"0953-816X","type":"print"},{"value":"1460-9568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,9]]},"assertion":[{"value":"2023-10-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}