{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:05:43Z","timestamp":1791288343997,"version":"4.3.0"},"reference-count":67,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:00:00Z","timestamp":1717977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    People with Parkinson's disease often exhibit improvements in motor tasks when exposed to external sensory cues. While the effects of different types of sensory cues on motor functions in Parkinson's disease have been widely studied, the underlying neural mechanism of these effects and the potential of sensory cues to alter the motor cortical activity patterns and functional connectivity of cortical motor areas are still unclear. This study aims to compare changes in oxygenated haemoglobin, deoxygenated haemoglobin and correlations among different cortical regions of interest during wrist movement under different external stimulus conditions between people with Parkinson's disease and controls. Ten Parkinson's disease patients and 10 age\u2010 and sex\u2010matched neurologically healthy individuals participated, performing repetitive wrist flexion and extension tasks under auditory and visual cues. Changes in oxygenated and deoxygenated haemoglobin in motor areas were measured using functional near\u2010infrared spectroscopy, along with electromyograms from wrist muscles and wrist movement kinematics. The functional near\u2010infrared spectroscopy data revealed significantly higher neural activity changes in the Parkinson's disease group's pre\u2010motor area compared to controls (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.006), and functional connectivity between the supplementary motor area and pre\u2010motor area was also significantly higher in the Parkinson's disease group when external sensory cues were present (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.016). These results indicate that external sensory cues' beneficial effects on motor tasks are linked to changes in the functional connectivity between motor areas responsible for planning and preparation of movements.\n                  <\/jats:p>","DOI":"10.1111\/ejn.16437","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T22:05:34Z","timestamp":1718057134000},"page":"4332-4345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Connecting the dots: Sensory cueing enhances functional connectivity between pre\u2010motor and supplementary motor areas in Parkinson's disease"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6052-9892","authenticated-orcid":false,"given":"Ali K.","family":"Zadeh","sequence":"first","affiliation":[{"name":"Department of Clinical Neurosciences, Cumming School of Medicine University of Calgary  Calgary Alberta 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