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Previous research has suggested that fronto\u2010parietal activities play a crucial role in WM. However, there remains no agreement on the effect of working memory load (WML) on neural activities and haemodynamic responses. Here, our study seeks to examine the effect of WML through simultaneous electroencephalography (EEG) and functional near\u2010infrared spectroscopy (fNIRS). In this study, a delay change detection task was conducted on 23 healthy volunteers. The task included three levels: one item, three items and five items. The EEG and fNIRS were simultaneously recorded during the task. Neural activities and haemodynamic responses at prefrontal and parietal regions were analysed using time\u2010frequency analysis and weighted phase\u2010lag index (wPLI). We observed a significant enhancement in prefrontal and parietal \u03b2 suppression as WML increased. Furthermore, as WML increased, there was a notable enhancement in fronto\u2010parietal connectivity (FPC), as evidenced by both EEG and fNIRS. Correlation analysis indicated that as WML increased, there was a potential for enhancement of neurovascular coupling (NVC) of FPC.<\/jats:p>","DOI":"10.1111\/ejn.16478","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T01:55:38Z","timestamp":1725328538000},"page":"5413-5427","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fronto\u2010parietal activity changes associated with changes in working memory load: Evidence from simultaneous electroencephalography and functional near\u2010infrared spectroscopy analysis"],"prefix":"10.1111","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-5267-3159","authenticated-orcid":false,"given":"Yu","family":"Wang","sequence":"first","affiliation":[{"name":"The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Health and Rehabilitation Science, School of Life Science and Technology Xi'an Jiaotong University  Xi'an Shaanxi P. 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