{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:44:00Z","timestamp":1772160240467,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100009053","name":"The Wellcome Trust DBT India Alliance","doi-asserted-by":"publisher","award":["IA\/S\/18\/2\/504003"],"award-info":[{"award-number":["IA\/S\/18\/2\/504003"]}],"id":[{"id":"10.13039\/501100009053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Aging alters brain structure and function, and studying such changes may help understand the neural basis underlying aging and devise interventions to detect deviations from healthy progression. Electroencephalogram (EEG) offers an effective way to study healthy aging owing to its high temporal resolution and affordability. Recent studies have shown that narrow\u2010band stimulus\u2010induced gamma oscillations (20\u201370\u2009Hz) in EEG, induced with Cartesian gratings in a fixation task paradigm, weaken with healthy aging and onset of Alzheimer's disease (\n                    <jats:sc>AD<\/jats:sc>\n                    ) while remaining highly reproducible for a given subject and thus hold promise as potential biomarkers. However, functional connectivity (FC) sometimes changes in a different way compared with sensor power with aging. This difference could be potentially addressed by studying how underlying gamma sources change with aging, since either a reduction in source power or a shrinkage of the sources (or both) could reduce the power in the sensors but may have different effects on other measures such as FC. We therefore reconstructed EEG gamma sources through a linear inverse method called exact low\u2010resolution tomography analysis (eLORETA) on a large (\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u2009217) cohort of healthy elderly subjects (&gt; 50\u2009years). We further characterized gamma distribution in cortical space as an exponential fall\u2010off from a seed voxel with maximal gamma source power to delineate a reduction in magnitude versus shrinkage. We found a significant reduction in magnitude but not shrinkage with healthy aging. Overall, our results shed light on changes in EEG gamma source distribution with healthy aging, which could provide clues about underlying neural mechanisms.\n                  <\/jats:p>","DOI":"10.1111\/ejn.70138","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T01:09:53Z","timestamp":1747271393000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Stimulus\u2010Induced Gamma Sources Reduce in Power but Not in Spatial Extent With Healthy Aging in Human EEG"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3816-6677","authenticated-orcid":false,"given":"Ankan","family":"Biswas","sequence":"first","affiliation":[{"name":"Centre for Neuroscience Indian Institute of Science  Bengaluru India"},{"name":"IISc Mathematics Initiative Indian Institute of Science  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7097-0414","authenticated-orcid":false,"given":"Wupadrasta\u00a0Santosh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Centre for Neuroscience Indian Institute of Science  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanishka","family":"Sharma","sequence":"additional","affiliation":[{"name":"Centre for Neuroscience Indian Institute of Science  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supratim","family":"Ray","sequence":"additional","affiliation":[{"name":"Centre for Neuroscience Indian Institute of Science  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/texcom\/tgad011"},{"key":"e_1_2_9_3_1","first-page":"187","article-title":"Structural Brain Changes in Aging: Courses, Causes and Cognitive Consequences","volume":"21","author":"Anders M. 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