{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:49:00Z","timestamp":1787014140446,"version":"build-2736575974"},"reference-count":78,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T00:00:00Z","timestamp":1749254400000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012456","name":"National Social Science Fund of China","doi-asserted-by":"publisher","award":["22BSH163"],"award-info":[{"award-number":["22BSH163"]}],"id":[{"id":"10.13039\/501100012456","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Externalizing behaviors are particularly pronounced in the context of psychopathy. Recent neurobiological models suggest that psychopathy may be associated with abnormalities in brain network connectivity, which could contribute to its development and its links to externalizing behaviors. However, the specific structural networks contributing to psychopathy and its relation to externalizing behaviors remain poorly understood. In this study, we investigated the structural connectivity associated with psychopathy and its relation to externalizing behaviors in 82 young adults from the MPI Leipzig Mind\u2010Brain\u2013Body dataset. A structural connectome\u2013based prediction model with leave\u2010one\u2010out cross\u2010validation identified both positive and negative networks associated with psychopathy. Specifically, the positive network involved regions related to social\u2010affective processing, language, and reward systems, while the negative network was associated with regions involved in attention modulation. Furthermore, mediation analyses revealed two potential neural pathways from psychopathic traits to externalizing behaviors via emotional processing and attention modulation networks. These findings suggest that alterations in structural connectivity play a significant role in psychopathy and may underlie the externalizing behaviors observed in individuals with the disorder.<\/jats:p>","DOI":"10.1111\/ejn.70158","type":"journal-article","created":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T07:24:25Z","timestamp":1749281065000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The Role of Structural Brain Networks in Psychopathy and Its Relation to Externalizing Behaviors"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4896-2263","authenticated-orcid":false,"given":"Peiyang","family":"Guo","sequence":"first","affiliation":[{"name":"State Key Laboratory of Cognitive Neuroscience and Learning &amp; IDG\/McGovern Institute for Brain Research Beijing Normal University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Education &amp; Institute of Applied Psychology Tianjin University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Education &amp; Institute of Applied Psychology Tianjin University  Tianjin China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,7]]},"reference":[{"key":"e_1_2_16_2_1","volume-title":"Manual for the ASEBA Adult Forms & Profiles","author":"Achenbach T. M.","year":"2003"},{"key":"e_1_2_16_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2017.149"},{"key":"e_1_2_16_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sdata.2018.308"},{"key":"e_1_2_16_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003\u2010024\u201007274\u20103"},{"key":"e_1_2_16_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2022.01.001"},{"key":"e_1_2_16_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0956797610396227"},{"key":"e_1_2_16_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010\u20100277(95)00676\u2010P"},{"key":"e_1_2_16_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579405050418"},{"key":"e_1_2_16_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291715000987"},{"key":"e_1_2_16_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2013.07.008"},{"key":"e_1_2_16_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2018.05.008"},{"key":"e_1_2_16_13_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579417000566"},{"key":"e_1_2_16_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bht089"},{"key":"e_1_2_16_15_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3372\u201013.2014"},{"key":"e_1_2_16_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.06.041"},{"key":"e_1_2_16_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22779"},{"key":"e_1_2_16_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2016.02.041"},{"key":"e_1_2_16_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2009.40"},{"key":"e_1_2_16_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2012.08.006"},{"key":"e_1_2_16_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2010.74"},{"key":"e_1_2_16_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.12.066"},{"key":"e_1_2_16_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41398\u2010020\u20100816\u20108"},{"key":"e_1_2_16_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2020.102402"},{"key":"e_1_2_16_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2016.10.020"},{"key":"e_1_2_16_26_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291721001525"},{"key":"e_1_2_16_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24028"},{"key":"e_1_2_16_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhw157"},{"key":"e_1_2_16_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073191115606205"},{"key":"e_1_2_16_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.23274"},{"key":"e_1_2_16_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2024.112809"},{"key":"e_1_2_16_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12144\u2010022\u201003242\u20104"},{"key":"e_1_2_16_33_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adc9970"},{"key":"e_1_2_16_34_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0039703"},{"key":"e_1_2_16_35_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.clinpsy.3.022806.091452"},{"key":"e_1_2_16_36_1","doi-asserted-by":"publisher","DOI":"10.1037\/bul0000040"},{"key":"e_1_2_16_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0072375"},{"key":"e_1_2_16_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.26626"},{"key":"e_1_2_16_39_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2636\u201014.2015"},{"key":"e_1_2_16_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/1073191113514105"},{"key":"e_1_2_16_41_1","doi-asserted-by":"publisher","DOI":"10.9758\/cpn.2021.19.1.63"},{"key":"e_1_2_16_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2024.108979"},{"key":"e_1_2_16_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep09426"},{"key":"e_1_2_16_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpsc.2016.07.004"},{"key":"e_1_2_16_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.1647"},{"key":"e_1_2_16_46_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.4540"},{"key":"e_1_2_16_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/sdata.2018.307"},{"key":"e_1_2_16_48_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4215\u201011.2011"},{"key":"e_1_2_16_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2018.01.024"},{"key":"e_1_2_16_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2009.07.035"},{"key":"e_1_2_16_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2004.10.016"},{"key":"e_1_2_16_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.03.012"},{"key":"e_1_2_16_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469\u20108986.1994.tb02440.x"},{"key":"e_1_2_16_54_1","first-page":"3","volume-title":"Handbook of Psychopathy","author":"Patrick C. J.","year":"2018"},{"key":"e_1_2_16_55_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0954579409000492"},{"key":"e_1_2_16_56_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0796\u201009.2009"},{"key":"e_1_2_16_57_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5010\u201014.2015"},{"key":"e_1_2_16_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380\u2010018\u20100122\u20105"},{"key":"e_1_2_16_59_1","unstructured":"R Core Team.2013. \u201cR: A Language and Environment for Statistical Computing.\u201d R Foundation for Statistical Computing.http:\/\/www.R\u2010project.org\/."},{"key":"e_1_2_16_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2018.11.025"},{"key":"e_1_2_16_61_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.11.1134"},{"key":"e_1_2_16_62_1","unstructured":"Revelle W..2023.Psych: Procedures for Psychological Psychometric and Personality Research. Northwestern University Evanston Illinois. R package version 2.3.9 https:\/\/CRAN.R\u2010project.org\/package=psych."},{"key":"e_1_2_16_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2006.07.021"},{"key":"e_1_2_16_64_1","doi-asserted-by":"publisher","DOI":"10.1177\/2167702616631495"},{"key":"e_1_2_16_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroling.2017.12.009"},{"key":"e_1_2_16_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201020583\u20105"},{"key":"e_1_2_16_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2014.07.018"},{"key":"e_1_2_16_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpsc.2018.04.002"},{"key":"e_1_2_16_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2016.178"},{"key":"e_1_2_16_70_1","doi-asserted-by":"publisher","DOI":"10.1037\/bul0000024"},{"key":"e_1_2_16_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2015.03.012"},{"key":"e_1_2_16_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2011.06.005"},{"key":"e_1_2_16_73_1","doi-asserted-by":"publisher","DOI":"10.3758\/s13415\u2010021\u201000891\u2010z"},{"key":"e_1_2_16_74_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617715001009"},{"key":"e_1_2_16_75_1","doi-asserted-by":"publisher","DOI":"10.1037\/neu0000448"},{"key":"e_1_2_16_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2017.01.014"},{"key":"e_1_2_16_77_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.22911"},{"key":"e_1_2_16_78_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/673165"},{"key":"e_1_2_16_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.04.027"}],"container-title":["European Journal of Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejn.70158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:14:16Z","timestamp":1749773656000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ejn.70158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":78,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1111\/ejn.70158"],"URL":"https:\/\/doi.org\/10.1111\/ejn.70158","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/EJN.70158\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.70158\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.70158\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.70158\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.70158\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.70158\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/EJN.70158\/v3\/decision1","asserted-by":"object"}]},"ISSN":["0953-816X","1460-9568"],"issn-type":[{"value":"0953-816X","type":"print"},{"value":"1460-9568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-03-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70158"}}