{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:17:04Z","timestamp":1791764224646,"version":"4.3.4"},"reference-count":53,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,9,14]],"date-time":"2025-09-14T00:00:00Z","timestamp":1757808000000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    While some studies have suggested that autonomous sensory meridian response (ASMR) can relieve anxiety, whether ASMR relieves anxiety in trait\u2010anxious individuals and its neural mechanisms remain a question worth exploring. We used the self\u2010threatening\n                    <jats:italic>n<\/jats:italic>\n                    \u2010back paradigm to elicit state anxiety and an ASMR video to relieve anxiety. Functional near\u2010infrared spectroscopy (fNIRS) was used to monitor frontal and temporal lobe activity to explore the neurophysiological changes when watching ASMR videos and then further explore the mechanism of self\u2010reported \u201cfeelings\u201d of ASMR. During the anxiety arousal phase, the hemodynamic responses (HR) of the middle frontal gyrus (MFG) and prefrontal cortex (PFC) were significantly enhanced in participants with high trait anxiety. Those with low\u2010trait anxiety had significantly reduced HR of the dorsolateral prefrontal cortex (DLPFC). Compared with the non\u2010ASMR video, the HR of the MFG, PFC, and DLPFC were significantly lower in participants who watched the ASMR video. When the experience of ASMR was reported, the HR of the premotor and auxiliary motor cortices, middle frontal lobe, and DLPFC were significantly reduced. While watching an ASMR video, brain activity is the opposite of when anxiety is elicited in people with high trait anxiety. The activated area when the participants were watching the ASMR video, and when they reported experiencing ASMR, overlapped with the anxiety\u2010related parts of the brain. This provides neurophysiological evidence of how an ASMR video can relieve anxiety.\n                  <\/jats:p>","DOI":"10.1111\/ejn.70251","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T06:33:04Z","timestamp":1757917984000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["An Exploratory Study on the Regulatory Effect of Autonomous Sensory Meridian Response on Anxiety: Evidence From Functional Near\u2010Infrared Brain Imaging Technology"],"prefix":"10.1111","volume":"62","author":[{"given":"Huan","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of psychology Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yating","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of psychology Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of psychology Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binjie","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of psychology Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiani","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of psychology Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HuiLing","family":"Li","sequence":"additional","affiliation":[{"name":"Shanghai Key Laboratory of Brain Functional Genomics (Ministry of Education), School of Psychology and Cognitive Science East China Normal University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of psychology Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3045-0198","authenticated-orcid":false,"given":"Qiang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of psychology Wenzhou Medical University  Wenzhou China"},{"name":"Lishui Second Hospital Affiliated to Wenzhou Medical University  Lishui China"},{"name":"Zhejiang Provincial Clinical Research Center for Mental Disorders, The Affiliated Kangning Hospital, Wenzhou Medical University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianghe","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of psychology Wenzhou Medical University  Wenzhou China"},{"name":"Zhejiang Provincial Clinical Research Center for Mental Disorders, The Affiliated Kangning Hospital, Wenzhou Medical University  Wenzhou China"},{"name":"Institute of Aging, Key Laboratory of Alzheimer's Disease of Zhejiang Province Wenzhou Medical University  Wenzhou China"},{"name":"Institute of Wenzhou Zhejiang University  Wenzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,14]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.22518"},{"issue":"4","key":"e_1_2_12_3_1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1097\/YIC.0000000000000078","article-title":"Efficacy of Treatments for Anxiety Disorders: A Meta\u2010Analysis","volume":"30","author":"Bandelow B.","year":"2015","journal-title":"International Clinical Psychopharmacology"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.851"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.3846"},{"issue":"3","key":"e_1_2_12_6_1","doi-asserted-by":"crossref","first-page":"571","DOI":"10.3758\/s13415-012-0100-3","article-title":"Trait Anxiety and the Neural Efficiency of Manipulation in Working Memory","volume":"12","author":"Basten U.","year":"2012","journal-title":"Cognitive, Affective, & Behavioral Neuroscience"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2012.06.003"},{"issue":"2","key":"e_1_2_12_8_1","first-page":"299","article-title":"False Recognition and State\/Trait Anxiety","volume":"34","author":"Beato M. 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