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We proposed that cerebellar\u2010cortical integration, which underlies motor adaptation, is related to the modulation of frequency\u2010specific oscillatory activity. We examined motor error and electrophysiological correlates (power spectrum and phase locking value analysis) measured during different sessions of transcranial alternating stimulation (tACS) delivered to the cerebellum at relevant frequencies (50\u2009Hz, 20\u2009Hz, or sham). We found that 50\u2009Hz tACS, but not 20\u2009Hz or sham stimulation, reduced movement error, especially in initial practice trials. Electroencephalography (EEG) analysis revealed modulation of spectral power and phase synchrony (wPLI) in frontal, parietal, and occipital regions, with specific patterns for both the frequency range and the task stage. Power and wPLI modulation under fifty Hz stimulation were associated with the magnitude of motor adaptation. Our findings suggest that frequency\u2010specific neural oscillations play a crucial role in the effective integration between the cerebellum and cortical regions of the brain. Significance: Our data indicate that cerebellar tACS at approximately 50\u2009Hz may serve as an effective neuromodulation strategy to enhance motor adaptation in humans, with specific neural correlates.<\/jats:p>","DOI":"10.1111\/ejn.70373","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T06:27:21Z","timestamp":1766730441000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cerebellar Transcranial Alternating Current Stimulation Accelerates Motor Adaptation via the Modulation of Cortical Synchrony"],"prefix":"10.1111","volume":"62","author":[{"given":"Juan\u00a0J.","family":"Mariman","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Faculty of Arts and Physical Education Universidad Metropolitana de Ciencias de la Educaci\u00f3n  Santiago Chile"},{"name":"Department of Physical Therapy, Faculty of Medicine Universidad de Chile  Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Rojas\u2010L\u00edbano","sequence":"additional","affiliation":[{"name":"Centro de Estudios en Neurociencia Humana y Neuropsicolog\u00eda, Facultad de Psicolog\u00eda Universidad Diego Portales  Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo\u00a0I.","family":"Burgos","sequence":"additional","affiliation":[{"name":"Department of Neurology Oregon Health &amp; Science University  Portland Oregon USA"},{"name":"Doctor of Physical Therapy Program George Fox University  Newberg Oregon USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoni","family":"Valero\u2010Cabr\u00e9","sequence":"additional","affiliation":[{"name":"Cerebral Dynamics, Plasticity and Rehabilitation Group, FRONTLAB, Centre de Recherche de l'Institut du Cerveau, CNRS UMR 7225, INSERM UMRS 1127 Universit\u00e9 Pierre et Marie Curie  Paris France"},{"name":"Cognitive Neuroscience and Information Technology Research Program Open University of Catalonia (UOC)  Barcelona Spain"},{"name":"Laboratory for Cerebral Dynamics Plasticity and Rehabilitation Boston University School of Medicine  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9895-7684","authenticated-orcid":false,"given":"Pedro\u00a0E.","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Department of Neuroscience. 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