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Although some neuroscientists may underrate the potential benefits of successful interdisciplinary collaborations, others may be unaware of the typical difficulties of such collaborations or are not trained in skills that render them fruitful. Here, we argue that interdisciplinary interactions have long been part of neuroscience, although they are often challenging, because neuroscientists may be confronted with concepts, assumptions, and interpretative horizons that differ from their own. This can lead to misunderstandings and little mutual appreciation. Using the historical development of brain imaging techniques, we distinguish between different types of interdisciplinary interactions and illustrate some of their benefits. In addition, we present various challenges for collaborations at the interface between traditional laboratory\u2010type approaches and those of clinical or computational neuroscience or of ecological field approaches. To address these challenges, we invite neuroscientists to consider philosophers as collaboration partners with complementary expertise, which includes special consideration of language use, underlying assumptions and proficiency in conceptual analysis. This expertise can be used by neuroscientists to increase their understanding and address some difficulties in interdisciplinary interactions more effectively. The benefits of these interactions can be expected to outweigh challenges in the dialogue with philosophers. Importantly, neuroscientists can choose between reading philosophical literature, participating in joint events with philosophers, and integrating philosophers into neuroscience projects. This may allow neuroscientists to explore unforeseen possibilities to improve or initiate collaborations with scientists from other fields and disciplines.<\/jats:p>","DOI":"10.1111\/ejn.70542","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T05:44:01Z","timestamp":1780897441000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["How to Foster Challenging Interdisciplinary Collaborations: Can Philosophy Support Neuroscientists?"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1813-7262","authenticated-orcid":false,"given":"M.","family":"Kunze","sequence":"first","affiliation":[{"name":"Department for Pathobiology of the Nervous System, Center for Brain Research Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Brun","sequence":"additional","affiliation":[{"name":"University of Bordeaux, CNRS, IMN, UMR 5293  Bordeaux France"},{"name":"Philosophy Department University Bordeaux Montaigne  Pessac France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Badaut","sequence":"additional","affiliation":[{"name":"Brain Molecular Imaging Lab, CNRS UMR 5536, RMSB, University of Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Darnaud\u00e9ry","sequence":"additional","affiliation":[{"name":"University of Bordeaux, INRAE, Bordeaux INP, NutriNeuro, UMR 1286  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Gross","sequence":"additional","affiliation":[{"name":"IMMUNOlogy From CONcepts and ExPeriments to Translation (ImmunoConcept), CNRS UMR 5164, University of Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Peltier","sequence":"additional","affiliation":[{"name":"University of Bordeaux, Interdisciplinary Institute for Neuroscience (IINS), CNRS UMR 5297  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Pradeu","sequence":"additional","affiliation":[{"name":"IMMUNOlogy From CONcepts and ExPeriments to Translation (ImmunoConcept), CNRS UMR 5164, University of Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3113-6392","authenticated-orcid":false,"given":"I.","family":"Sarto\u2010Jackson","sequence":"additional","affiliation":[{"name":"Konrad Lorenz Institute for Evolution and Cognition Research  Klosterneuburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7247-0472","authenticated-orcid":false,"given":"J. 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