{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:23:27Z","timestamp":1786116207791,"version":"build-2736575974"},"reference-count":53,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:00:00Z","timestamp":1784851200000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Alcohol consumption significantly impairs postural stability by disrupting vestibular function, increasing the risk of falls. This study investigated the feasibility of using galvanic vestibular stimulation (GVS) to mitigate alcohol\u2010induced postural instability in healthy adults, employing acute alcohol intake as a transient model of vestibular dysfunction. Sixty participants were assigned to groups with or without alcohol consumption (estimated blood alcohol concentration [BAC] 0.06%\u20130.08%) and randomly received one of three GVS types: random noise (rnGVS), direct current plus random noise (rn\u2010dcGVS), or a sham stimulation (fGVS). Static balance was assessed using a stabilometric platform with eyes closed on an unstable surface. As expected, alcohol consumption significantly worsened stabilometric parameters, resembling vestibular pathological hypofunction. fGVS produced no significant changes, ruling out a placebo effect. Notably, rnGVS significantly improved postural stability in subjects who consumed alcohol, reducing sway velocity, maximal anteroposterior (Max AP), and mediolateral displacements (Max ML) during and immediately after stimulation. In contrast, rn\u2010dcGVS worsened stability in subjects in the no alcohol consuming group with no significant change in the alcohol consuming group. These results demonstrate that rnGVS can effectively attenuate alcohol\u2010induced postural instability in a transient experimental model of vestibular dysfunction and support the use of acute alcohol intake as a controlled model for investigating vestibular modulation.<\/jats:p>","DOI":"10.1111\/ejn.70627","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T16:50:56Z","timestamp":1784911856000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring the Feasibility of Mitigating Alcohol\u2010Induced Instability Using Galvanic Vestibular Stimulation"],"prefix":"10.1111","volume":"64","author":[{"given":"Nancy","family":"Barranco","sequence":"first","affiliation":[{"name":"Instituto de Fisiolog\u00eda Benem\u00e9rita Universidad Aut\u00f3noma de Puebla  Puebla M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Arellano","sequence":"additional","affiliation":[{"name":"Instituto de Fisiolog\u00eda Benem\u00e9rita Universidad Aut\u00f3noma de Puebla  Puebla M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla","family":"Pineda","sequence":"additional","affiliation":[{"name":"Instituto de Fisiolog\u00eda Benem\u00e9rita Universidad Aut\u00f3noma de Puebla  Puebla M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Soto","sequence":"additional","affiliation":[{"name":"Instituto de Fisiolog\u00eda Benem\u00e9rita Universidad Aut\u00f3noma de Puebla  Puebla M\u00e9xico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Benavidez S.2021. \u201cEfecto de la Estimulaci\u00f3n El\u00e9ctrica de Campo (EEC) Sobre la Actividad de las Neuronas Aferentes Vestibulares en la Rata. Master in Sciences Thesis.\u201d Instituto de Fisiolog\u00eda Benem\u00e9rita Universidad Aut\u00f3noma de Puebla 2021."},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19073911"},{"key":"e_1_2_11_4_1","first-page":"17","volume-title":"Handbook of Clinical Neurology","author":"Cullen K. E.","year":"2016"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41583\u2010019\u20100153\u20101"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2017.00117"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2023.1218737"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00035.2019"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/1531\u20108249(199902)45:2<216::aid\u2010ana12>3.0.co;2\u2010f"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00008.2004"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00900"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.95861"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201053834\u20107"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep37575"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1109\/TVCG.2022.3150506"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES\u2010140513"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14942"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2020.109606"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnint.2014.00059"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.30.665"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2020.581405"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2017.10.007"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci10100740"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci14010015"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000001228"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221\u2010025\u201007079\u20108"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1037\/pha0000309"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2022.08.013"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18168678"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221\u2010011\u20102633\u2010z"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2022.109435"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024\u20103205(89)90150\u20101"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci13091333"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010025\u201007036\u20107"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.5152\/iao.2023.231030"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.15338"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES\u2010140520"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.3103\/S0027133021060054"},{"key":"e_1_2_11_39_1","first-page":"111","volume-title":"Teor\u00eda, Algoritmos y Aplicaciones en Computaci\u00f3n","author":"Salinas E.","year":"2009"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2014.11.019"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.4321\/S1135\u201057272014000400004"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415\u2010018\u20108814\u2010y"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2012.07.009"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2024.1159174"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.3389\/frspt.2024.1422868"},{"key":"e_1_2_11_46_1","unstructured":"Soto E. R.Vega E.Salinas andP.Robles.2014. \u201cPosturographic System Using a Balance Board (US Patent No. 8 672 861).\u201d US Patent and Trademark Office."},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2022.106430"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.3757\/jser.59.171"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.3109\/02699052.2011.607789"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES\u2010220211"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnint.2014.00004"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19116480"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415\u2010017\u20108481\u20104"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415\u2010023\u201012085\u20103"}],"container-title":["European Journal of Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejn.70627","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ejn.70627","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ejn.70627","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T08:23:28Z","timestamp":1786004608000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ejn.70627"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":53,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1111\/ejn.70627"],"URL":"https:\/\/doi.org\/10.1111\/ejn.70627","archive":["Portico"],"relation":{},"ISSN":["0953-816X","1460-9568"],"issn-type":[{"value":"0953-816X","type":"print"},{"value":"1460-9568","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-04-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70627"}}