{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T02:56:19Z","timestamp":1790564179404,"version":"4.1.0"},"reference-count":98,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T00:00:00Z","timestamp":1789862400000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["231095\u2010111021"],"award-info":[{"award-number":["231095\u2010111021"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Eur J of Neuroscience"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Spectral power decay (1\/\n                    <jats:italic>f<\/jats:italic>\n                    <jats:sup>\n                      <jats:italic>\u03b2<\/jats:italic>\n                    <\/jats:sup>\n                    ) of cortical activity has long been considered of low relevance to the understanding of brain function (e.g., associated with background noise of neuronal activity). However, growing literature suggests that it can reflect optimized spatiotemporal organization of neuronal activity across the cortex serving both cognition and behavior. Thus, clarifying the mechanisms underlying the regulation of this network property could have numerous impacts for the neuroscience field as well as for patients suffering from various neurological disorders with cognitive deficits linked to alterations in brain power decay properties. Using a constitutive knockout mouse and a multifractal wavelet\u2010leaders formalism, we here investigated the involvement of the synaptic adhesion molecule Neuroligin\u20102, which shapes synaptic inhibition and associates with neurodevelopmental diseases, in modulating spectral power decay properties of the electrocorticographic signal (i.e., the most prominent Hurst exponent \u201cHm\u201d and its local \u201cDispersion\u201d). Knockout mice showed increased Hm values across all wake and sleep states together with amplified daily dynamics during wake and paradoxical sleep, and increased Dispersion specifically for slow\u2010wave sleep in comparison with wild\u2010type littermates. Following a 6\u2010h sleep deprivation, Hm daily variations were more altered in knockout mice than controls for wake and paradoxical sleep, but less affected for slow\u2010wave sleep. Importantly, mutant mice display hypersynchronized epileptic\u2010like electrocorticographic events, which were characterized by further increases in Hm and Dispersion. These findings provide support for the involvement of Neuroligin\u20102 in shaping 1\/\n                    <jats:italic>f<\/jats:italic>\n                    <jats:sup>\n                      <jats:italic>\u03b2<\/jats:italic>\n                    <\/jats:sup>\n                    cortical activity properties and bring perspectives, notably, for neurodevelopmental conditions.\n                  <\/jats:p>","DOI":"10.1111\/ejn.70665","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:55:26Z","timestamp":1789952126000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Baseline Dynamics and Sleep Loss\u2013Driven Changes of Electrocorticographic Aperiodic Properties Are Altered in Mice Lacking Neuroligin\u20102"],"prefix":"10.1111","volume":"64","author":[{"given":"Tanya","family":"Leduc","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Facult\u00e9 de m\u00e9decine Universit\u00e9 de Montr\u00e9al  Montreal Quebec Canada"},{"name":"Centre de recherche du Centre hospitalier de l'Universit\u00e9 de Montr\u00e9al (CRCHUM)  Montreal Quebec Canada"},{"name":"Centre int\u00e9gr\u00e9 universitaire en sant\u00e9 et services sociaux du Nord\u2010de\u2010l'\u00cele\u2010de\u2010Montr\u00e9al (CIUSSS\u2010NIM)  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janine","family":"El Helou","sequence":"additional","affiliation":[{"name":"Centre int\u00e9gr\u00e9 universitaire en sant\u00e9 et services sociaux du Nord\u2010de\u2010l'\u00cele\u2010de\u2010Montr\u00e9al (CIUSSS\u2010NIM)  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"B\u00e9langer\u2010Nelson","sequence":"additional","affiliation":[{"name":"Centre int\u00e9gr\u00e9 universitaire en sant\u00e9 et services sociaux du Nord\u2010de\u2010l'\u00cele\u2010de\u2010Montr\u00e9al (CIUSSS\u2010NIM)  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0198-9426","authenticated-orcid":false,"given":"Cl\u00e9ment","family":"Bourguignon","sequence":"additional","affiliation":[{"name":"Centre de recherche du Centre hospitalier de l'Universit\u00e9 de Montr\u00e9al (CRCHUM)  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Marc","family":"Lina","sequence":"additional","affiliation":[{"name":"Centre int\u00e9gr\u00e9 universitaire en sant\u00e9 et services sociaux du Nord\u2010de\u2010l'\u00cele\u2010de\u2010Montr\u00e9al (CIUSSS\u2010NIM)  Montreal Quebec Canada"},{"name":"Centre de recherches math\u00e9matiques Universit\u00e9 de Montr\u00e9al  Montreal Quebec Canada"},{"name":"D\u00e9partement de g\u00e9nie \u00e9lectrique \u00c9cole de technologie sup\u00e9rieure  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6242-9166","authenticated-orcid":false,"given":"Val\u00e9rie","family":"Mongrain","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, Facult\u00e9 de m\u00e9decine Universit\u00e9 de Montr\u00e9al  Montreal Quebec Canada"},{"name":"Centre de recherche du Centre hospitalier de l'Universit\u00e9 de Montr\u00e9al (CRCHUM)  Montreal Quebec Canada"},{"name":"Centre int\u00e9gr\u00e9 universitaire en sant\u00e9 et services sociaux du Nord\u2010de\u2010l'\u00cele\u2010de\u2010Montr\u00e9al (CIUSSS\u2010NIM)  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593\u2010022\u201001214\u20102"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.abd8379"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsz210"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13041\u2010025\u201001186\u2010x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2015.06.016"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010018\u201007762\u20101"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.59.381"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13062\u2010023\u201000377\u20107"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601\u2010183X.2008.00455.x"},{"issue":"3","key":"e_1_2_12_11_1","first-page":"195","article-title":"A Two Process Model of Sleep Regulation","volume":"1","author":"Borb\u00e9ly A. 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