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Humans and barn owls both localize sounds accurately, yet they rely on fundamentally different cue configurations shaped by their ear anatomy and neural circuitry. In humans, symmetrical ears provide interaural time and level differences (ITD and ILD) for horizontal localization, while vertical localization depends primarily on high\u2010frequency, monaural spectral cues generated by the pinnae. Barn owls, by contrast, possess asymmetrical ears and use binaural cues for both azimuth and elevation. Because auditory pathways are tuned to species\u2010specific cue statistics, it remains unclear whether humans can adapt when binaural level cues are also made informative about elevation. We tested this by fitting human listeners with asymmetric ear molds that disrupted normal spectral cues, introduced elevation\u2010dependent ILDs, and left ITDs unaffected. Participants wore the molds during daily life and were tested with broadband, high\u2010pass, and low\u2010pass noise bursts. Acute mold exposure severely degraded elevation localization, whereas horizontal localization remained largely unaffected. With prolonged exposure, elevation localization improved, but adaptation was limited, variable across listeners, and fluctuated across sessions. Improvement was strongest for broadband sounds. Because broadband and high\u2010pass sounds both contained high\u2010frequency information, this broadband advantage cannot be explained by access to additional spectral cues alone. Instead, it suggests that low\u2010frequency ITDs helped listeners exploit the altered binaural cue structure, including the elevation\u2010dependent ILDs introduced by the molds. These findings show that humans can partially adapt to asymmetric outer\u2010ear acoustics when complementary spatial cues help resolve ambiguity in the altered cue structure.<\/jats:p>","DOI":"10.1111\/ejn.70685","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:51:13Z","timestamp":1790401873000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Partial Learning in Human Sound Localization With Asymmetric Ears"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1709-6224","authenticated-orcid":false,"given":"Peter","family":"Bremen","sequence":"first","affiliation":[{"name":"Department of Neuroscience Erasmus MC, University Medical Center Rotterdam  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2904-2195","authenticated-orcid":false,"given":"Robert F.","family":"van der Willigen","sequence":"additional","affiliation":[{"name":"Research Centre Innovations in Care, Data Supported Healthcare: Data\u2010Science Unit Rotterdam University of Applied Sciences  Rotterdam the Netherlands"},{"name":"School of Communication, Media and Information Technology Rotterdam University of Applied Sciences  Rotterdam the Netherlands"},{"name":"Centre of Expertise HRTech Rotterdam University of Applied Sciences  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5957-5712","authenticated-orcid":false,"given":"A. 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