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The present study examined learning\u2010associated changes in brain complexity during the execution of a sequential arm movement following augmented\u2010feedback\u2010based practice. Thirty\u2010eight healthy young adults practiced a sequential arm movement with augmented feedback across five sessions. Cortical activity was recorded with electroencephalography during the first and last practice sessions. Multiscale entropy was used to quantify brain complexity across 50 time scales. Behavioral measures indicated improved movement accuracy and reduced dual\u2010task costs across practice. At the cortical level, a significant global decrease in entropy was observed from the first to the last practice session. Further analyses revealed that the differences were confined to coarse temporal window and midline frontal electrodes Fz and FCz. In addition, changes in coarse\u2010scale entropy at FCz were negatively correlated with reductions in absolute error. Together, the present findings suggest that augmented\u2010feedback\u2010based practice is accompanied by a refinement of cortical complexity during movement execution, particularly in large\u2010scale frontal dynamics. Multiscale entropy may therefore provide a sensitive framework for capturing learning\u2010related neural adaptations that complement conventional electroencephalographic measures and advance the understanding of motor learning at the systems level.<\/jats:p>","DOI":"10.1111\/ejn.70729","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:00:27Z","timestamp":1792670427000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reduced Brain Complexity During the Execution of a Sequential Arm Movement Following an Augmented\u2010Feedback\u2010Based Practice: A Multiscale Entropy Analysis"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3358-4669","authenticated-orcid":false,"given":"Daghan","family":"Piskin","sequence":"first","affiliation":[{"name":"Department Sports &amp; Health, Exercise Science &amp; Neuroscience Paderborn University  Paderborn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5972-612X","authenticated-orcid":false,"given":"Linda","family":"Margraf","sequence":"additional","affiliation":[{"name":"Department Sports &amp; Health, Psychology and Movement Science Paderborn University  Paderborn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Weigelt","sequence":"additional","affiliation":[{"name":"Department Sports &amp; Health, Psychology and Movement Science Paderborn University  Paderborn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2683-5826","authenticated-orcid":false,"given":"Jochen","family":"Baumeister","sequence":"additional","affiliation":[{"name":"Department Sports &amp; Health, Exercise Science &amp; Neuroscience Paderborn University  Paderborn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/00222895.1971.10734898"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.793298"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10548\u2010023\u201000976\u20107"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102202\u201015\u2010102"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2517\u20106161.1995.tb02031.x"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2004.10.003"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2019.02.008"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2025.109098"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/e23030304"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2017.07.002"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsycho.2020.107849"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.89.068102"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.71.021906"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2016.09.004"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2001.0976"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.10.008"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2016.01.001"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0028\u20103932(02)00158\u20106"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.14439"},{"key":"e_1_2_11_21_1","volume-title":"Human Performance","author":"Fitts P. 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