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Here, we employ a three\u2010step framework to study microclimate influence on ectotherm host thermal behaviour, focusing on amphibian chytridiomycosis in fire salamanders (\n                    <jats:italic>Salamandra salamandra<\/jats:italic>\n                    ) infected with the fungal pathogen\n                    <jats:italic>Batrachochytrium salamandrivorans<\/jats:italic>\n                    (\n                    <jats:italic>Bsal<\/jats:italic>\n                    ). Laboratory trials reveal that innate variation in thermal preference, rather than behavioural fever, can inhibit infection and facilitate salamander recovery under humidity\u2010saturated conditions. Yet, a 3\u2010year field study and a mesocosm experiment close to the invasive\n                    <jats:italic>Bsal<\/jats:italic>\n                    range show that microclimate constraints suppress host thermal behaviour favourable to disease control. A final mechanistic model, that estimates range\u2010wide, year\u2010round host body temperature relative to microclimate, suggests that these constraints are rule rather than exception. Our results demonstrate how innate host defences against epizootics may remain constrained in the wild, which predisposes to range\u2010wide disease outbreaks and population declines.\n                  <\/jats:p>","DOI":"10.1111\/ele.13616","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T13:40:50Z","timestamp":1601991650000},"page":"27-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Microclimate limits thermal behaviour favourable to disease control in a nocturnal amphibian"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5839-7683","authenticated-orcid":false,"given":"Wouter","family":"Beukema","sequence":"first","affiliation":[{"name":"Wildlife Health Ghent Department of Pathology, Bacteriology and Avian Diseases Ghent University Salisburylaan 133 Merelbeke 9820 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Pasmans","sequence":"additional","affiliation":[{"name":"Wildlife Health Ghent Department of Pathology, Bacteriology and Avian Diseases Ghent University Salisburylaan 133 Merelbeke 9820 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Van Praet","sequence":"additional","affiliation":[{"name":"Wildlife Health Ghent Department of Pathology, Bacteriology and Avian Diseases Ghent University Salisburylaan 133 Merelbeke 9820 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Ferri\u2010Y\u00e1\u00f1ez","sequence":"additional","affiliation":[{"name":"Department of Community Ecology Helmholtz Centre for Environmental Research (UFZ) Theodor\u2010Lieser\u2010Strasse 4 Halle 06120 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moira","family":"Kelly","sequence":"additional","affiliation":[{"name":"Wildlife Health Ghent Department of Pathology, Bacteriology and Avian Diseases Ghent University Salisburylaan 133 Merelbeke 9820 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra E.","family":"Laking","sequence":"additional","affiliation":[{"name":"Wildlife Health Ghent Department of Pathology, Bacteriology and Avian Diseases Ghent University Salisburylaan 133 Merelbeke 9820 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"Erens","sequence":"additional","affiliation":[{"name":"Wildlife Health Ghent Department of Pathology, Bacteriology and Avian Diseases Ghent University Salisburylaan 133 Merelbeke 9820 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen","family":"Speybroeck","sequence":"additional","affiliation":[{"name":"Research Institute for Nature and Forest \u2010 INBO Havenlaan 88 bus 73 Brussels 1000 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kris","family":"Verheyen","sequence":"additional","affiliation":[{"name":"Forest &amp; Nature Lab Department of Forest and Water Management Ghent University Geraardsbergsesteenweg 267 Gontrode 9090 Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Lens","sequence":"additional","affiliation":[{"name":"Terrestrial Ecology Unit Ghent University, K. 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