{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:28:19Z","timestamp":1788827299691,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,1,8]],"date-time":"2013-01-08T00:00:00Z","timestamp":1357603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Both vertebrobasilar dolichoectasia (<jats:styled-content style=\"fixed-case\">VBD<\/jats:styled-content>) and cerebral microbleeds (<jats:styled-content style=\"fixed-case\">CMB<\/jats:styled-content>s) are related with the risk of intracerebral hemorrhage. We aimed to examine the relationship between the <jats:styled-content style=\"fixed-case\">VBD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CMB<\/jats:styled-content> in ischaemic stroke patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A consecutive series of 182 patients hospitalized because of ischaemic stroke or transient ischaemic attack (<jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>), and who underwent gradient echo brain magnetic resonance imaging were retrospectively recruited from a prospective stroke registry. <jats:styled-content style=\"fixed-case\">CMB<\/jats:styled-content> locations were categorized into anterior and posterior circulation. Ectasia was defined as basilar artery (<jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content>) diameter &gt;\u20054.5\u2005mm, and dolichosis, as either <jats:styled-content style=\"fixed-case\">BA<\/jats:styled-content> bifurcation above the suprasellar cistern or lateral to the margin of the clivus or dorsum sellae. Whether <jats:styled-content style=\"fixed-case\">VBD<\/jats:styled-content> is associated with <jats:styled-content style=\"fixed-case\">CMB<\/jats:styled-content> anywhere in the brain or in anterior or posterior circulation territories was analysed using binary and multinomial logistic regression models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010four subjects (13.2%) had <jats:styled-content style=\"fixed-case\">VBD<\/jats:styled-content> and 48 (26.4%) had <jats:styled-content style=\"fixed-case\">CMB<\/jats:styled-content>s. <jats:styled-content style=\"fixed-case\">CMB<\/jats:styled-content>s were more frequently observed in patients with <jats:styled-content style=\"fixed-case\">VBD<\/jats:styled-content> than without (66.7% vs. 20.3%, <jats:italic>P\u2005<\/jats:italic>&lt;\u20050.001). <jats:styled-content style=\"fixed-case\">VBD<\/jats:styled-content> was significantly associated with <jats:styled-content style=\"fixed-case\">CMB<\/jats:styled-content>s in any location (crude odds ratio, 7.88; 95% confidence interval, 3.10\u201320.02), in the posterior circulation territory only (9.63; 2.60\u201334.94), and in both territories (9.25; 3.40\u201326.29), but not in the anterior circulation only (1.14; 0.009\u201311.20). These associations remained unchanged after adjusting for age, gender, hypertension, leukoaraiosis and stroke subtype.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">VBD<\/jats:styled-content> in patients with ischaemic stroke or <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content> is independently associated with <jats:styled-content style=\"fixed-case\">CMB<\/jats:styled-content>s, especially in the posterior circulation territory.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12075","type":"journal-article","created":{"date-parts":[[2013,1,8]],"date-time":"2013-01-08T16:36:20Z","timestamp":1357662980000},"page":"824-830","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Vertebrobasilar dolichoectasia as a risk factor for cerebral microbleeds"],"prefix":"10.1111","volume":"20","author":[{"given":"J.\u2010M.","family":"Park","sequence":"first","affiliation":[{"name":"Department of Neurology Eulji General Hospital Eulji University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.\u2010S.","family":"Koo","sequence":"additional","affiliation":[{"name":"Department of Neurology Seoul Saint Mary Hospital Catholic University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.\u2010K.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology Eulji General Hospital Eulji University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Neurology Eulji General Hospital Eulji University Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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