{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T13:21:21Z","timestamp":1758979281239},"reference-count":21,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T00:00:00Z","timestamp":1367798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Patients with transient ischaemic attack (<jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>) with a high risk of imminent stroke can be identified with the <jats:styled-content style=\"fixed-case\">ABCD<\/jats:styled-content><jats:sup>2<\/jats:sup> score and findings on <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> angiography. The predictive value of transcranial color\u2010coded sonography (<jats:styled-content style=\"fixed-case\">TCCS<\/jats:styled-content>) has not been evaluated in this setting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis was conducted of patients consecutively treated for <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content> or minor stroke in a <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content> clinic within 24\u00a0h of symptom onset. Agreement between <jats:styled-content style=\"fixed-case\">TCCS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> three\u2010dimensional time\u2010of\u2010flight images for the diagnosis of proximal (internal carotid artery, vertebral artery, basilar artery, circle of Willis and main stem of the middle cerebral artery) &gt;50% stenosis or occlusion of the intracranial symptomatic artery was evaluated. The sensitivity, specificity, predictive values and likelihood ratio of <jats:styled-content style=\"fixed-case\">TCCS<\/jats:styled-content> for predicting recurrent <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>\/stroke at 7\u00a0days were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 159 patients with a <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content> or minor stroke within the last 24\u00a0h, 142 had a readable acoustic temporal bone window (89.3%). <jats:styled-content style=\"fixed-case\">TCCS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> were performed within 4\u00a0h of each other in 116 patients. <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> showed a symptomatic proximal intracranial steno\u2010occlusive lesion in six patients. Agreement between <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TCCS<\/jats:styled-content> was perfect (\u03ba coefficient\u00a0=\u00a01). Recurrent <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>\/stroke occurred in 10 patients (eight <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content> and two minor strokes). All recurrences occurred within 24\u00a0h of symptom onset. A symptomatic proximal intracranial steno\u2010occlusive lesion was found on <jats:styled-content style=\"fixed-case\">TCCS<\/jats:styled-content> in 4\/10 patients with recurrence and 3\/132 patients without recurrence [sensitivity\u00a040%; specificity\u00a097.7%; likelihood ratio\u00a018.1; odds ratio (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) adjusted for <jats:styled-content style=\"fixed-case\">ABCD<\/jats:styled-content><jats:sup>2<\/jats:sup> score 31.5 (4.5\u2013218.6)].<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study shows that <jats:styled-content style=\"fixed-case\">TCCS<\/jats:styled-content> can be used to guide triage of patients with <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12178","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T11:55:27Z","timestamp":1367841327000},"page":"1212-1217","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Transcranial color\u2010coded sonography to predict recurrent transient ischaemic attack\/stroke"],"prefix":"10.1111","volume":"20","author":[{"given":"N.","family":"Nasr","sequence":"first","affiliation":[{"name":"Department of Vascular Neurology UMR U1048 University of Toulouse Toulouse"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Ssi\u2010Yan\u2010Kai","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Toulouse University Hospital Toulouse"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Guidolin","sequence":"additional","affiliation":[{"name":"Department of Vascular Neurology Toulouse University Hospital Toulouse"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Bonneville","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology UMR U825 University of Toulouse Toulouse"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Larrue","sequence":"additional","affiliation":[{"name":"Department of Vascular Neurology UMR U1048 University of Toulouse Toulouse"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,5,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66702-5"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60150-0"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000249007.12256.4a"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.571174"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.571844"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.578971"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4949.2008.00182.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20497"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.591099"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.637421"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3144"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000163561.90680.1C"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2292030516"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.1.87"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.555169"},{"key":"e_1_2_7_17_1","first-page":"360","article-title":"Understanding interobserver agreement: the kappa statistic","volume":"37","author":"Viera AJ","year":"2005","journal-title":"Fam Med"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.488833"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.30.9.1819"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000035285.43467.FF"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000087933"},{"key":"e_1_2_7_22_1","first-page":"386","article-title":"The effect of contrast material on transcranial Doppler evaluation of normal middle cerebral artery peak systolic velocity","volume":"21","author":"Khan HG","year":"2000","journal-title":"AJNR Am J Neuroradiol"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fene.12178","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.12178","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T12:18:21Z","timestamp":1696249101000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.12178"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,6]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/ene.12178"],"URL":"https:\/\/doi.org\/10.1111\/ene.12178","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,6]]},"assertion":[{"value":"2013-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-03-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-05-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}