{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T02:50:49Z","timestamp":1791946249373,"version":"4.3.4"},"reference-count":20,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2013,6,21]],"date-time":"2013-06-21T00:00:00Z","timestamp":1371772800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Korea Health 21 R&D Project"},{"name":"Ministry of Health"},{"name":"Welfare and Family Affairs"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Along with intracranial atherosclerotic disease (<jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content>), moyamoya disease (<jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content>) is the most common cause of middle cerebral artery (<jats:styled-content style=\"fixed-case\">MCA<\/jats:styled-content>) occlusion in Asians. Although they have differing vascular wall pathologies, conventional angiographic evaluation methods cannot easily differentiate <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> from <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content> in certain situations, such as in young patients with atherosclerotic risk factors. High resolution magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) findings for the diseased segments of <jats:styled-content style=\"fixed-case\">MCA<\/jats:styled-content>s in <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> and symptomatic <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content> were compared to further elucidate differences in arterial wall changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Angiographically confirmed patients, 12 <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> and 20 <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content>, who suffered a stroke due to <jats:styled-content style=\"fixed-case\">MCA<\/jats:styled-content> occlusion were recruited and underwent <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>. The size of the outer diameter and other stenotic vessel wall characteristics revealed by <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>, including enhancement, eccentricity and other lesion patterns, were analyzed by two independent reviewers in a blind fashion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> patients were younger than <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content> patients (32.92\u00a0\u00b1\u00a011.08\u00a0years vs. 51.85\u00a0\u00b1\u00a011.97\u00a0years; mean\u00a0\u00b1\u00a0<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) and displayed a smaller outer diameter in the stenotic portion (1.61\u00a0\u00b1\u00a00.43\u00a0mm for <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> vs. 3.03\u00a0\u00b1\u00a00.53\u00a0mm for <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content>,<jats:italic> P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001). Eccentric lesions (three of 12 in <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> vs. 19 of 20 in <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content>,<jats:italic> P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001) and focal enhancements in diseased areas (two of seven in <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> vs. 13 of 17 in <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content>,<jats:italic> P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.061) were less common in <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> findings show that <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> is associated with smaller, concentric occlusive lesions which are rarely enhanced compared with symptomatic <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content>, consistent with the results of previous pathological reports. <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> may therefore have utility in differentiating <jats:styled-content style=\"fixed-case\">MMD<\/jats:styled-content> from <jats:styled-content style=\"fixed-case\">ICAD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12202","type":"journal-article","created":{"date-parts":[[2013,6,21]],"date-time":"2013-06-21T16:20:56Z","timestamp":1371831656000},"page":"1311-1318","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":116,"title":["High resolution <scp>MRI<\/scp> difference between moyamoya disease and intracranial atherosclerosis"],"prefix":"10.1111","volume":"20","author":[{"given":"Y. J.","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Neuroradiology Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Y.","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Neurology Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. W.","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Neurology Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. C.","family":"Suh","sequence":"additional","affiliation":[{"name":"Neuroradiology Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. S.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. U.","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Neurology Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.32.883"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-8467(97)00032-2"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0303-8467(97)00082-6"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2441051769"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.10030"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2008.10.019"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000225074.47396.71"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000342470.69739.b3"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000157667.06542.b7"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198705283162204"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199405193302008"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc0802.104327"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.47.1"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-012-1472-4"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199901143400207"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.14.1.50"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.3171\/2009.1.FOCUS08310"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nic.2005.08.005"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2011.20"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2008.00272.x"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fene.12202","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.12202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T15:52:51Z","timestamp":1696348371000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.12202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,21]]},"references-count":20,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["10.1111\/ene.12202"],"URL":"https:\/\/doi.org\/10.1111\/ene.12202","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,21]]},"assertion":[{"value":"2013-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-04-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-06-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}