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Only two clinic\u2010based studies showed that <jats:styled-content style=\"fixed-case\">TGA<\/jats:styled-content> patients had a higher frequency of migraine history. Our population\u2010based study aimed to investigate whether migraine patients were associated with a higher risk of developing <jats:styled-content style=\"fixed-case\">TGA<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with migraine aged \u226518\u00a0years were identified from the Taiwan National Health Insurance Research Database between 2005 and 2009. Each migraine patient was randomly matched to one subject without migraine or other headache disorders based on age, sex and cardiovascular comorbidities. Patients with antecedent stroke, epilepsy or <jats:styled-content style=\"fixed-case\">TGA<\/jats:styled-content> were excluded. Both cohorts were followed up until the end of 2010. The incidence rates of <jats:styled-content style=\"fixed-case\">TGA<\/jats:styled-content> were compared and risk factors were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 158\u00a0301 patients in the migraine cohort and 158\u00a0301 patients in the matched control cohort were enrolled. During a mean follow\u2010up of 3.0\u00a0years (range 0\u20136\u00a0years), the migraine cohort had a greater risk of developing TGA than the control cohort [7.59 vs. 3.06 per 100\u00a0000 person\u2010years, incidence rate ratio (<jats:styled-content style=\"fixed-case\">IRR<\/jats:styled-content>)\u00a0=\u00a02.48, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.002]. Compared with the matched cohort, only female migraine patients aged 40\u201360\u00a0years showed a significantly higher risk of TGA [IRR\u00a0=\u00a03.18 (1.31\u20138.82), <jats:italic>P<\/jats:italic>\u00a0=\u00a00.005]. Of note, the incidence rates did not differ between migraine patients with and without aura.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This population\u2010based study demonstrates that migraine is associated with an increased risk of <jats:styled-content style=\"fixed-case\">TGA<\/jats:styled-content>, particularly in female patients aged 40\u201360\u00a0years.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12346","type":"journal-article","created":{"date-parts":[[2014,2,13]],"date-time":"2014-02-13T11:37:28Z","timestamp":1392291448000},"page":"718-724","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Migraine is associated with a higher risk of transient global amnesia: a nationwide cohort study"],"prefix":"10.1111","volume":"21","author":[{"given":"K.\u2010H.","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Medicine Taipei Veterans General Hospital Taoyuan 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