{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T22:06:43Z","timestamp":1785708403827,"version":"3.56.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T00:00:00Z","timestamp":1397001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"funder":[{"name":"Norwegian Neuromuscular Disorders Foundation, Neuromuscular Disorders Association, Norway"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Comorbidity in myasthenia gravis (MG) is important for diagnosis, treatment and prognosis. Disease complexity was assessed by examining total drug treatment, immune therapy and comorbidity in a complete national MG cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All recipients of the MG\u2010specific drug pyridostigmine 2004\u20132010 registered in the compulsory Norwegian Prescription Database who met the inclusion criteria were included. The pyridostigmine group was compared with the general Norwegian population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Myasthenia gravis patients received co\u2010medication more often than the controls for nearly all groups of medication, including insulins (95% confidence interval 2.0\u20133.7), thyroid therapy (1.7\u20132.5), antidepressants (1.3\u20131.7), anti\u2010infectives (1.2\u20131.4), lipid\u2010modifying agents (1.1\u20131.4) and immunomodulating agents (6.8\u20138.8).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Myasthenia gravis patients are more often treated with non\u2010MG prescription drugs than controls, reflecting frequent co\u2010medication and comorbidity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12439","type":"journal-article","created":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T08:18:48Z","timestamp":1397031528000},"page":"948-955","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Total drug treatment and comorbidity in myasthenia gravis: a population\u2010based cohort study"],"prefix":"10.1111","volume":"21","author":[{"given":"J. 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