{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T02:29:03Z","timestamp":1776479343670,"version":"3.51.2"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T00:00:00Z","timestamp":1396396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Idiopathic intracranial hypertension (<jats:styled-content style=\"fixed-case\">IIH<\/jats:styled-content>), also known as pseudotumor cerebri, is a disorder related to increased intracranial pressure without clinical, laboratory or radiological evidence of an intracranial space occupying lesion or cerebral sinus vein thrombosis, predominantly affecting obese women of childbearing age. Our aim was to determine the incidence and clinical features of <jats:styled-content style=\"fixed-case\">IIH<\/jats:styled-content> in Israel.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a cross\u2010sectional study, all medical records of patients discharged from the hospital with a primary diagnosis of <jats:styled-content style=\"fixed-case\">IIH<\/jats:styled-content> during 2005\u20132007 were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four hundred and twenty\u2010eight patients with a new onset of <jats:styled-content style=\"fixed-case\">IIH<\/jats:styled-content> were diagnosed. The average annual incidence rate was 2.02 per 100\u00a0000 with an incidence of 3.17 per 100\u00a0000 for women and 0.85 per 100\u00a0000 for men. The incidence rate in females of childbearing age (18\u201345) was 5.49 per 100\u00a0000. The female to male ratio for &gt;17\u00a0years old was 6.1:1 (252 females and 41 males) and 2.1:1 (60 females and 28 males) for ages 11\u201317. Obesity was documented in 83.4% of patients. Body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) data were available for 159 (37.1%) patients; of these, 59.1% had a <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>\u00a0\u2265\u00a030.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The incidence of <jats:styled-content style=\"fixed-case\">IIH<\/jats:styled-content> in Israel has increased during the last decade. This finding could be related to the increasing rates of obesity. The association of <jats:styled-content style=\"fixed-case\">IIH<\/jats:styled-content> and obesity should be further explored especially with regard to the effect of weight reduction for primary prevention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12442","type":"journal-article","created":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T14:36:26Z","timestamp":1396449386000},"page":"1055-1059","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["The incidence of idiopathic intracranial hypertension in Israel from 2005 to 2007: results of a nationwide survey"],"prefix":"10.1111","volume":"21","author":[{"given":"A.","family":"Kesler","sequence":"first","affiliation":[{"name":"Neuro\u2010ophthalmology Unit Department of Ophthalmology Tel\u2010Aviv Sourasky Medical Center Tel Aviv Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Stolovic","sequence":"additional","affiliation":[{"name":"Neuro\u2010ophthalmology Unit Department of Ophthalmology Tel\u2010Aviv Sourasky Medical Center Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Bluednikov","sequence":"additional","affiliation":[{"name":"Israel Center for Disease Control Ministry of Health Tel Hashomer Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Shohat","sequence":"additional","affiliation":[{"name":"Israel Center for Disease Control Ministry of Health Tel Hashomer Israel"},{"name":"Department of Epidemiology and Preventive Medicine Sackler Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-97-2-249"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000029570.69134.1B"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1988.00520320065016"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)61045-3"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-200103000-00003"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.03.020"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-200103000-00004"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000333254.84120.f5"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2004.05.009"},{"key":"e_1_2_8_11_1","first-page":"387","article-title":"Pseudotumor cerebri \u2013 idiopathic intracranial hypertension in the pediatric population","volume":"3","author":"Kesler A","year":"2006","journal-title":"Pediatr Endocrinol Rev"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.41.2_Part_1.239"},{"key":"e_1_2_8_13_1","first-page":"155","article-title":"Idiopathic intracranial hypertension. 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