{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:42:08Z","timestamp":1790426528643,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,7,10]],"date-time":"2014-07-10T00:00:00Z","timestamp":1404950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Bilateral globus pallidus deep brain stimulation (<jats:styled-content style=\"fixed-case\">GP<\/jats:styled-content>i\u2010<jats:styled-content style=\"fixed-case\">DBS<\/jats:styled-content>) represents an effective and relatively safe therapy for different forms of refractory dystonia. The aim of this study was to assess, retrospectively, the effect of two different stimulation settings during <jats:styled-content style=\"fixed-case\">GP<\/jats:styled-content>i\u2010<jats:styled-content style=\"fixed-case\">DBS<\/jats:styled-content> in 22 patients affected by primary generalized or multi\u2010segmental dystonia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirteen patients were stimulated using a voltage\u2010controlled setting whilst in the other nine patients a current\u2010controlled setting was used. Clinical features were evaluated for each patient at baseline, 6\u00a0months and 12\u00a0months after surgery by means of the Burke\u2212Fahn\u2212Marsden Dystonia Rating Scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Globus pallidus deep brain stimulation was effective in all patients. However, comparing constant\u2010current and constant\u2010voltage stimulation, a better outcome was found in the current\u2010controlled group during the last 6 months of follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Current\u2010controlled stimulation is effective during <jats:styled-content style=\"fixed-case\">GP<\/jats:styled-content>i\u2010<jats:styled-content style=\"fixed-case\">DBS<\/jats:styled-content> for primary dystonia and it could be a better choice than voltage\u2010controlled stimulation over long\u2010term follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12515","type":"journal-article","created":{"date-parts":[[2014,7,10]],"date-time":"2014-07-10T12:47:43Z","timestamp":1404996463000},"page":"919-926","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Clinical outcome of deep brain stimulation for dystonia: constant\u2010current or constant\u2010voltage stimulation? 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