{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:59:30Z","timestamp":1792011570077,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T00:00:00Z","timestamp":1410134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Our purpose was to determine the association of cataract surgery with subsequent development of dementia in older adults with newly diagnosed cataract.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>By using data from Taiwan National Health Insurance Research Database (<jats:styled-content style=\"fixed-case\">NHIRD<\/jats:styled-content>), a population\u2010based cohort study including 491\u00a0226 subjects aged 70 or older with first\u2010time diagnosis of cataract coded from 2000 to 2009 was conducted. After matching cataract patients receiving cataract surgery with cataract patients without receiving cataract surgery for age, sex, index date, Charlson Comorbidity Index score, interval between first coding of cataract diagnosis and index date, hypertension and diabetes mellitus, 113\u00a0123 patients in each cohort were enrolled. The main outcome measure was newly diagnosed dementia coded by neurologists or psychiatrists more than 365\u00a0days after cataract surgery. Incidence rate and hazard ratio of dementia were compared between the cataract surgery and cataract diagnosis cohorts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence rate of dementia was 22.40 per 1000 person\u2010years in the cataract surgery cohort and 28.87 per 1000 person\u2010years in the cataract diagnosis cohort. The rate of dementia was significantly lower in the cataract surgery group (hazard ratio 0.77, 95% confidence interval 0.75\u22120.79, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Female gender (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and a shorter interval between the date of first coding of a cataract diagnosis and the date of cataract surgery (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.009) were significantly associated with a lower incidence rate of dementia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In an <jats:styled-content style=\"fixed-case\">NHIRD<\/jats:styled-content> cohort of Taiwanese aged 70\u00a0years and older with a diagnosis of cataract, patients undergoing cataract surgery were associated with a reduced risk of subsequent dementia compared with those without cataract surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12561","type":"journal-article","created":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T04:47:19Z","timestamp":1410151639000},"page":"1370","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Cataract surgery is associated with a reduced risk of dementia: a nationwide population\u2010based cohort study"],"prefix":"10.1111","volume":"22","author":[{"given":"W.\u2010K.","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Taipei Veterans General Hospital Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.\u2010T.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Medicine Taipei City Hospital Heping Fuyou Branch Taipei Taiwan"},{"name":"Faculty of Medicine National Yang Ming University School of Medicine Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.\u2010J.","family":"Wang","sequence":"additional","affiliation":[{"name":"Faculty of Medicine National Yang Ming University School of Medicine Taipei Taiwan"},{"name":"Department of Neurology Neurological Institute Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Institute of Brain Science National Yang\u2010Ming University Taipei Taiwan"},{"name":"Brain Research Center National Yang\u2010Ming University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.\u2010C.","family":"Kuo","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases Department of Medicine Taipei Veterans General Hospital Taipei Taiwan"},{"name":"Institute of Clinical Medicine National Yang\u2010Ming University School of Medicine Taipei Taiwan"},{"name":"National Institute of Infectious Diseases and Vaccinology National Health Research Institutes Miaoli Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.\u2010C.","family":"Shia","sequence":"additional","affiliation":[{"name":"Graduate School of Business Administration Fu Jen Catholic University Taipei Taiwan"},{"name":"Department of Statistics and Information Science and Applied Statistics Fu Jen Catholic University Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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