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Most common comorbidities are thyroid disease, systemic lupus erythematosus and rheumatoid arthritis. Cardiomyositis and subclinical heart dysfunction have been described in patients with thymoma <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> and late onset <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> but represent no major threat. A thymic lymphoepithelioma implies an increased risk for another cancer. Autoimmune <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> represents no distinct cancer risk factor, although lymphomas and a few other cancer types have been reported with slightly increased frequency. Severe <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content>\u2010related muscle weakness means a risk for respiratory failure and respiratory tract infection. Drug <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> treatment can lead to side\u2010effects. Thymectomy is regarded as a safe procedure both short and long term. Non\u2010<jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content>\u2010related comorbidity represents a diagnostic and therapeutic challenge, especially in elderly patients. Diagnostic accuracy and optimal follow\u2010up is necessary to identify and treat all types of coexisting disease in <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/ene.12599","type":"journal-article","created":{"date-parts":[[2014,10,30]],"date-time":"2014-10-30T09:28:36Z","timestamp":1414661316000},"page":"17-23","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":135,"title":["Myasthenia gravis and risks for comorbidity"],"prefix":"10.1111","volume":"22","author":[{"given":"N. 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