{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T06:05:02Z","timestamp":1784873102976,"version":"3.55.0"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,11,29]],"date-time":"2014-11-29T00:00:00Z","timestamp":1417219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Hormonal and mechanical factors might increase the risk for cervical artery dissection (CAD) during pregnancy and the puerperium. There is uncertainty how to counsel women with a previous CAD regarding the risk of CAD recurrence during pregnancy and the puerperium.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In an observational study of four stroke centers, all women aged 16\u201345\u00a0years with primary CAD in the previous decade were asked to participate in a standardized assessment on long\u2010term follow\u2010up with a special focus on pregnancies and recurrent CAD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010two women were identified and 53 of them were included in the analysis (60%). Eleven women declined to participate, 28 were untraceable. The 39 non\u2010participants did not differ from participants regarding key baseline characteristics. Average follow\u2010up time was 72\u00a0months. Nine women (17%) had recurrent CAD after a median of 14\u00a0days (range 2\u00a0days to 117\u00a0months). Eleven women (20%) had a total of 13 completed pregnancies at a median of 44\u00a0months (range 12\u201384\u00a0months) after index CAD. Two of the pregnant women (18%) had suffered recurrent CAD \u226518\u00a0months prior to the pregnancy. All 13 pregnancies and puerperia went without recurrent CADs or cerebrovascular events. This includes giving birth by vaginal delivery (<jats:italic>n<\/jats:italic>\u00a0=\u00a06) and caesarean section (<jats:italic>n<\/jats:italic>\u00a0=\u00a07). None of the five women with typical connective tissue disease became pregnant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our observation suggests that the risk of recurrent CAD may not be greatly increased with pregnancies starting at least 12\u00a0months after CAD in women without typical connective tissue disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12602","type":"journal-article","created":{"date-parts":[[2014,11,29]],"date-time":"2014-11-29T10:15:44Z","timestamp":1417256144000},"page":"736-739","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Risk of recurrent cervical artery dissection during pregnancy, childbirth and puerperium"],"prefix":"10.1111","volume":"22","author":[{"given":"M.","family":"Reinhard","sequence":"first","affiliation":[{"name":"Department of Neurology University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Munz","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.\u2010L.","family":"von Kannen","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Freiburg Freiburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.\u2010J.","family":"Griesser\u2010Leute","sequence":"additional","affiliation":[{"name":"Department of Neurology Lahr\u2010Ettenheim Clinical Center Lahr Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Dittrich","sequence":"additional","affiliation":[{"name":"Department of Neurology University of M\u00fcnster M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. T.","family":"Engelter","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center University of Basel Basel Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,11,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1111\/ene.12228","article-title":"Etiology of first\u2010ever ischaemic stroke in European young adults: the 15 cities young stroke study","volume":"20","author":"Yesilot BN","year":"2013","journal-title":"Eur J Neurol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.510107"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000094325.95097.86"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70084-5"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000265595.50915.1e"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fene.12602","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.12602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T12:02:44Z","timestamp":1717588964000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.12602"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,29]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/ene.12602"],"URL":"https:\/\/doi.org\/10.1111\/ene.12602","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,29]]},"assertion":[{"value":"2014-06-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-09-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-11-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}