{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:15:03Z","timestamp":1789143303157,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>The risk of recurrence of stroke after pregnancy is poorly known.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was an observational study of women younger than 45\u00a0years of age with transient ischaemic attack (<jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>), cerebral infarction (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>), cerebral venous thrombosis (<jats:styled-content style=\"fixed-case\">CVT<\/jats:styled-content>) or intracerebral hemorrhage (<jats:styled-content style=\"fixed-case\">ICH<\/jats:styled-content>) treated in a stroke unit (January 1996\u20132011). The clinical data were prospectively collected in a database. Information on reproductive history after stroke was obtained using telephone surveys (2011). The variables were demographic data, vascular risk factors, stroke type, outcomes, medical advice concerning pregnancies after stroke, number of pregnancies after stroke, neurological assessment during pregnancy, antithrombotic treatments during pregnancy\/puerperium, fertility treatments administered and information about hemorrhagic\/ischaemic stroke recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 102 women were included: 24 <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>, 64 <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> (four large vessel disease, 14 cardioembolic, 12 small vessel disease, 17 undetermined etiology, 17 uncommon etiology), 12 <jats:styled-content style=\"fixed-case\">CVT<\/jats:styled-content> and two <jats:styled-content style=\"fixed-case\">ICH<\/jats:styled-content>. Mean age at the time of first stroke was 35 (\u00b17.5) years. Median follow\u2010up was 7.4\u00a0years (range 1\u201317). Thirty\u2010two pregnancies occurred in 27 patients (previous diagnosis: four <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>, 17 <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>, five <jats:styled-content style=\"fixed-case\">CVT<\/jats:styled-content> and one <jats:styled-content style=\"fixed-case\">ICH<\/jats:styled-content>). One woman became pregnant using <jats:italic>in vitro<\/jats:italic> fertilization. Only eight pregnancies were followed up by a neurologist. Of 26 pregnancies without previous history of <jats:styled-content style=\"fixed-case\">ICH<\/jats:styled-content>, 18 (62%) underwent preventive antithrombotic treatment. No recurrence of stroke was observed during pregnancy\/puerperium. Of the women without pregnancies after the first cerebrovascular event, four <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>s and three <jats:styled-content style=\"fixed-case\">TIA<\/jats:styled-content>s were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The recurrence of stroke after pregnancy is very low, which should be considered when counseling these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12630","type":"journal-article","created":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T04:51:21Z","timestamp":1422852681000},"page":"681","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Recurrence of stroke amongst women of reproductive age: impact of and on subsequent pregnancies"],"prefix":"10.1111","volume":"22","author":[{"given":"A.","family":"Cruz\u2010Herranz","sequence":"first","affiliation":[{"name":"Department of Neurology and Stroke 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