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The purpose of the current study was to make an unbiased assessment of which cerebral areas are affected in first\u2010ever acute ischaemic stroke patients identified as having language and speech impairments according to the National Institutes of Health Stroke Scale (<jats:styled-content style=\"fixed-case\">NIHSS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from 34 patients with language and speech impairment, with a score of 1\u20133 on item 9 of the <jats:styled-content style=\"fixed-case\">NIHSS<\/jats:styled-content>, following ischaemic stroke were collected from the Lund Stroke Register. Magnetic resonance images acquired up to 20\u00a0days after stroke onset were used to create an overlap lesion image using <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>cron software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The classical language areas, Wernicke's and Broca's areas, were affected in less than one\u2010fourth of the patients. The most frequently affected region was a subcortical region \u2013 the left caudate nucleus and the adjacent corona radiata.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings contribute to the growing body of evidence that the basal ganglia have a crucial role in the control over language and speech processing.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12822","type":"journal-article","created":{"date-parts":[[2015,8,13]],"date-time":"2015-08-13T04:25:44Z","timestamp":1439439944000},"page":"148-153","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Predominance of caudate nucleus lesions in acute ischaemic stroke patients with impairment in language and speech"],"prefix":"10.1111","volume":"23","author":[{"given":"E. O.","family":"Gr\u00f6nholm","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Lund, Neurology Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. C.","family":"Roll","sequence":"additional","affiliation":[{"name":"Department of Linguistics and Phonetics Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Horne","sequence":"additional","affiliation":[{"name":"Department of Linguistics and Phonetics Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. C.","family":"Sundgren","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology Lund University Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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