{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T00:49:36Z","timestamp":1776473376827,"version":"3.51.2"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,1,12]],"date-time":"2016-01-12T00:00:00Z","timestamp":1452556800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Gating of sensory evoked potentials (<jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content>s) around the onset of a voluntary movement is a physiological phenomenon with centripetal and central components, and may reflect sensorimotor integration required for normal movement control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Our objective was the investigation of <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> suppression at the onset of movement and the interaction between <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> suppression and vibration of the limb.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fourteen patients with primary focal\/segmental dystonia and 17 age\u2010matched healthy volunteers were studied. <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content>s were elicited after electrical stimulation of the median nerve at the wrist. Electroencephalograms (<jats:styled-content style=\"fixed-case\">EEG<\/jats:styled-content>s) were recorded over the scalp at three sites according to the International 10\u201320 System (F3, C3 and P3). <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content>s were recorded in four conditions: at rest, at the onset of movement (a self\u2010paced abduction movement of the right thumb), both in the absence and in the presence of vibration of the limb.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Repeated measures <jats:sc>anova<\/jats:sc> revealed that there was a significant main effect of group [<jats:italic>F<\/jats:italic>(1, 11.1) = 0.471, <jats:italic>P<\/jats:italic> = 0.002]. <jats:italic>Post hoc<\/jats:italic> exploration of this effect revealed it to be due to an absence of <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> suppression at movement onset in patients (mean ratio <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> movement onset\/rest 1.15 at F3, 1.13 at C3, 1.01 at P3) compared to controls, who had <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> suppression at movement onset (mean ratio <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> movement onset\/rest 0.79 at F3, 0.78 at C3, 0.77 at P3). With vibration, <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> suppression reduced in both patients and controls to a similar extent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These results demonstrate abnormal <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> suppression at the onset of movement in patients with primary dystonia, and in addition that vibration of the limb reduces <jats:styled-content style=\"fixed-case\">SEP<\/jats:styled-content> suppression in patients and controls.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12890","type":"journal-article","created":{"date-parts":[[2016,1,12]],"date-time":"2016-01-12T14:24:49Z","timestamp":1452608689000},"page":"562-568","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Abnormal movement\u2010related suppression of sensory evoked potentials in upper limb dystonia"],"prefix":"10.1111","volume":"23","author":[{"given":"A.","family":"Macerollo","sequence":"first","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"},{"name":"Department of Neuroscience and Sense Organs Aldo Moro University of Bari Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C.","family":"Chen","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"},{"name":"Neuroscience Laboratory, Department of Neurology China Medical University Hospital Taichung Taiwan"},{"name":"School of Medicine China Medical University Taichung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Parees","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Sadnicka","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Kassavetis","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. P.","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Kilner","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. C.","family":"Rothwell","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. J.","family":"Edwards","sequence":"additional","affiliation":[{"name":"Sobell Department of Motor Neuroscience and Movement Disorders UCL Institute of Neurology London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,12]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"351","article-title":"Dystonia: the spectrum of the disease","volume":"55","author":"Marsden CD","year":"1976","journal-title":"Res Publ Assoc Res Nerv Ment Dis"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/119.2.569"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380203"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/104.3.465"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4958-11.2012"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.9.1813"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.12.2179"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.8.1794"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380206"},{"key":"e_1_2_7_11_1","volume-title":"Mammalian Muscle Receptors and Their Central Actions","author":"Matthews PBC","year":"1972"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/113.3.691"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200008030-00002"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2013.00173"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3415-12.2013"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10339-013-0571-3"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870090408"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-5597(89)90049-X"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.1.42"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fene.12890","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fene.12890","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.12890","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ene.12890","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.12890","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T10:26:47Z","timestamp":1694428007000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.12890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1,12]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1111\/ene.12890"],"URL":"https:\/\/doi.org\/10.1111\/ene.12890","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,1,12]]},"assertion":[{"value":"2015-03-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-09-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-01-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}