{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T02:29:55Z","timestamp":1726453795257},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,25]],"date-time":"2016-01-25T00:00:00Z","timestamp":1453680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100006020","name":"Center for Translational Molecular Medicine","doi-asserted-by":"publisher","award":["01C\u2010202"],"award-info":[{"award-number":["01C\u2010202"]}],"id":[{"id":"10.13039\/501100006020","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Conjugate eye deviation (<jats:styled-content style=\"fixed-case\">CED<\/jats:styled-content>) and horizontal skew deviation are often seen in patients with intracerebral hemorrhage (<jats:styled-content style=\"fixed-case\">ICH<\/jats:styled-content>), but its prognostic significance is unclear. In this study, the association between brain scan assessed eye position and hospital mortality in patients with supratentorial ICH was tested.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis was performed in 316 patients with supratentorial <jats:styled-content style=\"fixed-case\">ICH<\/jats:styled-content>. Eye position was measured on first brain computed tomography or magnetic resonance imaging. Patients with <jats:styled-content style=\"fixed-case\">CED<\/jats:styled-content>, horizontal skew deviation or no deviation were distinguished. The association between eye position and hospital mortality was assessed using logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Conjugate eye deviation was present in 96 (30.4%), skew deviation in 44 (13.9%) and no deviation in 176 (55.7%) patients. In patients with <jats:styled-content style=\"fixed-case\">CED<\/jats:styled-content>, 81.3% had an eye position to the ipsilateral side of the hemorrhage. In univariable regression analysis, skew deviation was associated with mortality (odds ratio 3.10, 95% confidence interval 1.57\u20136.11; <jats:italic>P<\/jats:italic> = 0.001). In multivariable regression analysis, adjusting for age, <jats:styled-content style=\"fixed-case\">ICH<\/jats:styled-content> volume, intraventricular extension and Glasgow Coma Scale, eye position was not independently associated with mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Horizontal skew eyes were found to be an unfavorable prognostic factor. However, this was not independent of other important predictors of <jats:styled-content style=\"fixed-case\">ICH<\/jats:styled-content> mortality and is most probably explained by its association with worse initial clinical presentation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.12951","type":"journal-article","created":{"date-parts":[[2016,1,25]],"date-time":"2016-01-25T05:32:47Z","timestamp":1453699967000},"page":"831-835","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Association between eye position on brain scan and hospital mortality in acute intracerebral hemorrhage"],"prefix":"10.1111","volume":"23","author":[{"given":"K. J. 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