{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T12:56:40Z","timestamp":1789736200890,"version":"4.0.1"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,5,11]],"date-time":"2016-05-11T00:00:00Z","timestamp":1462924800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009362","name":"South London and Maudsley NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009362","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009360","name":"King\u2019s College London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009360","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Impulse control disorders (<jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>s) in Parkinson's disease (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>) are associated primarily with dopamine agonist (<jats:styled-content style=\"fixed-case\">DA<\/jats:styled-content>) use. Comparative surveys of clinical occurrence of impulse control behaviours on longer acting\/transdermal <jats:styled-content style=\"fixed-case\">DA<\/jats:styled-content> therapy across age ranges are lacking. The aim of this study was to assess the occurrence of <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>s in <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> patients across several European centres treated with short\u2010 or long\u2010acting [ropinirole (ROP); pramipexole (PPX)] and transdermal [rotigotine skin patch (<jats:styled-content style=\"fixed-case\">RTG<\/jats:styled-content>)] DAs, based on clinical survey as part of routine clinical care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A survey based on medical records and clinical interviews of patients initiating or initiated on <jats:styled-content style=\"fixed-case\">DA<\/jats:styled-content> treatment (both short\u2010 and long\u2010acting, and transdermal) across a broad range of disease stages and age groups was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four hundred and twenty\u2010five cases were included [mean age 68.3 years (range 37\u201390), mean duration of disease 7.5 years (range 0\u201337)]. <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content> frequencies (as assessed by clinical interview) were significantly lower with <jats:styled-content style=\"fixed-case\">RTG<\/jats:styled-content> (4.9%; <jats:italic>P<\/jats:italic> &lt; 0.05) compared with any other assessed <jats:styled-content style=\"fixed-case\">DA<\/jats:styled-content>s except for prolonged release PPX (<jats:styled-content style=\"fixed-case\">PPX<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content>). The rate of <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>s for <jats:styled-content style=\"fixed-case\">PPX<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PR<\/jats:styled-content> (6.6%) was significantly lower than for immediate release PPX (PPX\u2010IR) (19.0%; <jats:italic>P<\/jats:italic> &lt; 0.05). Discontinuation rates of <jats:styled-content style=\"fixed-case\">DA<\/jats:styled-content> therapy due to <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>s were low.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our data suggest a relatively low rate of <jats:styled-content style=\"fixed-case\">ICD<\/jats:styled-content>s with long\u2010acting or transdermal <jats:styled-content style=\"fixed-case\">DA<\/jats:styled-content>s, however these preliminary observational data need to be confirmed with prospective studies controlling for possible confounding factors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.13034","type":"journal-article","created":{"date-parts":[[2016,5,11]],"date-time":"2016-05-11T23:49:34Z","timestamp":1463010574000},"page":"1255-1261","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":96,"title":["A European multicentre survey of impulse control behaviours in Parkinson's disease patients treated with short\u2010 and long\u2010acting dopamine agonists"],"prefix":"10.1111","volume":"23","author":[{"given":"A.","family":"Rizos","sequence":"first","affiliation":[{"name":"King's College Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sauerbier","sequence":"additional","affiliation":[{"name":"King's College Hospital London UK"},{"name":"King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Antonini","sequence":"additional","affiliation":[{"name":"Parkinson and Movement Disorders Unit IRCCS Hospital San Camillo Venice and University of Padua Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Weintraub","sequence":"additional","affiliation":[{"name":"Perelman School of Medicine at the University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Martinez\u2010Martin","sequence":"additional","affiliation":[{"name":"National Center of Epidemiology and CIBERNED Carlos III Institute of Health Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Kessel","sequence":"additional","affiliation":[{"name":"King's College Hospital Princess Royal University Hospital site Orpington UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Henriksen","sequence":"additional","affiliation":[{"name":"University Hospital of Bispebjerg Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Falup\u2010Pecurariu","sequence":"additional","affiliation":[{"name":"County Emergency Clinic Hospital Faculty of Medicine Transilvania University Brasov Brasov Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Silverdale","sequence":"additional","affiliation":[{"name":"Greater Manchester Neuroscience Centre Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Durner","sequence":"additional","affiliation":[{"name":"King's College Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"R\u00f8kenes Karlsen","sequence":"additional","affiliation":[{"name":"King's College Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Grilo","sequence":"additional","affiliation":[{"name":"King's College Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Odin","sequence":"additional","affiliation":[{"name":"University of Lund Lund Sweden"},{"name":"University Hospital Reinkenheide Bremerhaven Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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