{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,9]],"date-time":"2024-05-09T09:49:06Z","timestamp":1715248146927},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,12,7]],"date-time":"2016-12-07T00:00:00Z","timestamp":1481068800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Paroxysmal atrial fibrillation (<jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>) is often asymptomatic and increases the risk of ischaemic stroke. Detection of <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> is challenging but crucial because a change of treatment decreases the risk of ischaemic stroke. Post\u2010stroke investigations recommend at least 24\u2010h continuous cardiac rhythm monitoring. Extended monitoring detects more <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> but is limited by costs due to manual analysis. Interpretive software might be a reasonable screening tool. The aim was to validate the performance and utility of Pathfinder <jats:styled-content style=\"fixed-case\">SL<\/jats:styled-content> software compared to manual analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In all, 135 ischaemic stroke patients with no prior history of <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> or atrial fibrillation and who had done a 7\u2010day continuous electrocardiogram monitoring (Holter) were included. Manual analysis was compared with Pathfinder <jats:styled-content style=\"fixed-case\">SL<\/jats:styled-content> software including a systematic control of registered events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventeen (12.6%) patients were diagnosed with <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> (atrial fibrillation &gt; 30 s). Pathfinder <jats:styled-content style=\"fixed-case\">SL<\/jats:styled-content> software including a systematic control of events registered 16 (94.1%) patients with <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>. Manually 15 (88.2%) patients were detected with <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content>. Pathfinder <jats:styled-content style=\"fixed-case\">SL<\/jats:styled-content> had a negative predictive value of 99% and sensitivity of 94%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Pathfinder <jats:styled-content style=\"fixed-case\">SL<\/jats:styled-content> software including a systematic evaluation of events is an acceptable alternative compared to manual analysis in <jats:styled-content style=\"fixed-case\">PAF<\/jats:styled-content> detection following ischaemic stroke. It is less time consuming and therefore a reliable, cheaper alternative compared to manual analysis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.13199","type":"journal-article","created":{"date-parts":[[2016,12,8]],"date-time":"2016-12-08T04:46:49Z","timestamp":1481172409000},"page":"322-325","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Semi\u2010automatic software based detection of atrial fibrillation in acute ischaemic stroke and transient ischaemic attack"],"prefix":"10.1111","volume":"24","author":[{"given":"M. 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