{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T16:14:58Z","timestamp":1782836098058,"version":"3.54.5"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,16]],"date-time":"2017-10-16T00:00:00Z","timestamp":1508112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Cognitive impairment is one of the most disabling non\u2010motor symptoms of Parkinson's disease. Mild cognitive impairment constitutes a major risk for the development of Parkinson's disease dementia in the course of the disease. A Movement Disorder Society Task Force proposed diagnostic criteria for mild cognitive impairment in Parkinson's disease (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>), comprising two operational levels: Level I and Level <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>. The objective of our study was to test the accuracy of Level I versus Level <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> diagnostic criteria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010six consecutive patients with Parkinson's disease were screened and 68 patients without dementia or depression were included in the study. We used the Montreal Cognitive Assessment, Mini\u2010Mental State Examination and Addenbrooke's Cognitive Evaluation\u2010R screening tools for Level I and an extensive neuropsychological battery for Level <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> assessment. We first diagnosed <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content> on the basis of Level <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> assessment and then calculated sensitivity, specificity and area under the receiver\u2013operator characteristics curve, comparing the performance of the three screening batteries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>None of the three screening batteries proposed for Level I assessment provided satisfactory combined sensitivity and specificity for detecting <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>, and their performance was similar. Using the Level <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> criteria, 29 patients (43%) were diagnosed as having <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>. Lowest cut\u2010off levels that provided at least 80% sensitivity were 24 for the Montreal Cognitive Assessment, 29 for the Mini\u2010Mental State Examination and 87 for the Addenbrooke's Cognitive Evaluation\u2010R. However, specificity levels were below 80% at these cut\u2010off levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We conclude that Level I assessment alone using screening batteries is not sufficiently sensitive\/specific to detect <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">MCI<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.13467","type":"journal-article","created":{"date-parts":[[2017,9,20]],"date-time":"2017-09-20T16:26:40Z","timestamp":1505924800000},"page":"148-153","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["An assessment of Movement Disorder Society Task Force diagnostic criteria for mild cognitive impairment in Parkinson's disease"],"prefix":"10.1111","volume":"25","author":[{"given":"P.","family":"Uysal\u2010Cant\u00fcrk","sequence":"first","affiliation":[{"name":"Behavioral Neurology and Movement Disorders Unit Department of Neurology, Istanbul Faculty of Medicine Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. A.","family":"Hana\u011fas\u0131","sequence":"additional","affiliation":[{"name":"Behavioral Neurology and Movement Disorders Unit Department of Neurology, Istanbul Faculty of Medicine Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6032-0856","authenticated-orcid":false,"given":"B.","family":"Bilgi\u00e7","sequence":"additional","affiliation":[{"name":"Behavioral Neurology and Movement Disorders Unit Department of Neurology, Istanbul Faculty of Medicine Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"G\u00fcrvit","sequence":"additional","affiliation":[{"name":"Behavioral Neurology and Movement Disorders Unit Department of Neurology, Istanbul Faculty of Medicine Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Emre","sequence":"additional","affiliation":[{"name":"Behavioral Neurology and Movement Disorders Unit Department of Neurology, Istanbul Faculty of Medicine Istanbul University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10280"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20216"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21507"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2009.07.007"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.58.12.1985"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23823"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21956"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.3.387"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.24893"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.51.6.745"},{"key":"e_1_2_6_12_1","first-page":"163","article-title":"Turkish version of the Beck Anxiety Inventory: psychometric properties","volume":"12","author":"Ulusoy M","year":"1998","journal-title":"J Cogn Psychother"},{"key":"e_1_2_6_13_1","first-page":"261","article-title":"Epworth uykululuk \u00f6l\u00e7e\u011finin ge\u00e7erli\u011fi ve g\u00fcvenirli\u011fi","volume":"10","author":"A\u011farg\u00fcn MY","year":"1999","journal-title":"T\u00fcrk Psikiyatri Dergisi"},{"key":"e_1_2_6_14_1","first-page":"62","article-title":"Geriatrik depresyon \u00f6l\u00e7e\u011finin t\u00fcrk ya\u015fli populasyonunda ge\u00e7erlik ve g\u00fcvenirli\u011fi","volume":"34","author":"Ertan T","year":"1997","journal-title":"N\u00f6ropsikiyatri Ar\u015fivi"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25426"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25655"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2014.01.009"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26084"},{"key":"e_1_2_6_19_1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.parkreldis.2014.10.020","article-title":"Assessing the utility of the Movement Disorder Society Task Force Level 1 diagnostic criteria for mild cognitive impairment in Parkinson's disease","volume":"21","author":"Szeto Jennifer YY","year":"2015","journal-title":"Parkinsonism Relat Disord"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mdc3.12391"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31829c5c86"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617715000041"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25875"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2013.2110"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2013.08.008"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.8.1427"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53221.x"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181fc29c9"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181c34b47"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000434309.85312.19"},{"key":"e_1_2_6_31_1","first-page":"25","article-title":"Evaluation of the diagnostic test's performance and their comparisons","volume":"32","author":"Dirican A","year":"2001","journal-title":"Cerrahpa\u015fa J Med"},{"key":"e_1_2_6_32_1","first-page":"260","article-title":"Tan\u0131 testlerinin de\u011ferlendirimesinde ROC (Receiver Operating Characteristics) e\u011frisinin kullan\u0131m\u0131","volume":"3","author":"Kan\u0131k EA","year":"2003","journal-title":"Mersin \u00dcniversitesi T\u0131p Fak\u00fcltesi Dergisi"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fene.13467","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.13467","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:28:47Z","timestamp":1695569327000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.13467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,16]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1111\/ene.13467"],"URL":"https:\/\/doi.org\/10.1111\/ene.13467","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,16]]},"assertion":[{"value":"2017-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-09-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}