{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T01:13:49Z","timestamp":1788225229302,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T00:00:00Z","timestamp":1539561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>In contrast to anterior circulation stroke (<jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content>), there is no evidence from randomized trials that mechanical thrombectomy (<jats:styled-content style=\"fixed-case\">MT<\/jats:styled-content>) with modern stent retrievers or thromboaspiration is safe and effective in posterior circulation stroke (<jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The present analysis was based on the prospective multicentre Registry on Revascularization in Ischemic Stroke Patients (<jats:styled-content style=\"fixed-case\">REVASK<\/jats:styled-content>) in Germany. Demographic data, periprocedural times and complications, recanalization rates, and functional outcome at discharge and after 3 months were compared between 139 consecutive patients with <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> (84.9% basilar artery, 16.5% vertebral artery and 4.3% posterior cerebral artery occlusion) and 961 patients with <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content> treated with <jats:styled-content style=\"fixed-case\">MT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> PCS<\/jats:styled-content> patients were significantly younger (65 vs. 69 years, <jats:italic>P<\/jats:italic> = 0.021) and had a lower median National Institutes of Health Stroke Scale (<jats:styled-content style=\"fixed-case\">NIHSS<\/jats:styled-content>) score at baseline (12 vs. 15, <jats:italic>P<\/jats:italic> = 0.024). Patients with <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> had a significantly longer time delay between symptom onset and both start and end of the <jats:styled-content style=\"fixed-case\">MT<\/jats:styled-content> procedure. Successful recanalization and thrombectomy passes did not significantly differ between the two groups. No symptomatic intracranial haemorrhage occurred in <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> compared to 3% in <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content> (<jats:italic>P<\/jats:italic> = 0.010). The median <jats:styled-content style=\"fixed-case\">NIHSS<\/jats:styled-content> score at discharge was 3 in <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> and 4 in <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content>. Favourable functional outcome at 3 months (modified Rankin Scale 0\u20132 38.0% vs. 42.6%, <jats:italic>P<\/jats:italic> = 0.392) and mortality (33.7% vs. 30.8%, <jats:italic>P<\/jats:italic> = 0.539) did not differ significantly between <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The study suggests that <jats:styled-content style=\"fixed-case\">MT<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> shows a lower risk of symptomatic intracranial haemorrhage and similar effectiveness compared to <jats:styled-content style=\"fixed-case\">ACS<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">PCS<\/jats:styled-content> patients also seem to benefit from <jats:styled-content style=\"fixed-case\">MT<\/jats:styled-content> started beyond 6 h after symptom onset.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.13809","type":"journal-article","created":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T13:18:13Z","timestamp":1537103893000},"page":"299-305","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":98,"title":["Thrombectomy in posterior circulation stroke: differences in procedures and outcome compared to anterior circulation stroke in the prospective multicentre <scp>REVASK<\/scp> registry"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5486-7027","authenticated-orcid":false,"given":"R.","family":"Weber","sequence":"first","affiliation":[{"name":"Departments of Neurology Alfried Krupp Krankenhaus Essen and Ruhr University Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Minnerup","sequence":"additional","affiliation":[{"name":"University Hospital M\u00fcnster M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Nordmeyer","sequence":"additional","affiliation":[{"name":"Department of Radiology and Neuroradiology Alfried Krupp Krankenhaus Essen Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Eyding","sequence":"additional","affiliation":[{"name":"University Hospital Knappschaftskrankenhaus Bochum and Klinikum Dortmund Dortmund Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2965-4051","authenticated-orcid":false,"given":"C.","family":"Krogias","sequence":"additional","affiliation":[{"name":"University Hospital St Josef\u2010Hospital Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Hadisurya","sequence":"additional","affiliation":[{"name":"Departments of Neurology Alfried Krupp Krankenhaus Essen and Ruhr University Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Berger","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology and Social Medicine University of M\u00fcnster M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the REVASK investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.112.652420"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g3175"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)00163-X"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1706442"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70173-5"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-310250"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.24336"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.116.012619"},{"key":"e_1_2_6_10_1","first-page":"404","article-title":"The \u2018Neurovascular Net Ruhr\u2019. 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