{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T02:24:03Z","timestamp":1774405443597,"version":"3.50.1"},"reference-count":16,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,3,5]],"date-time":"2019-03-05T00:00:00Z","timestamp":1551744000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Antibodies to myelin oligodendrocyte glycoprotein (MOG) have been identified in both children and adults with demyelination, with a strong association with bilateral or recurrent optic neuritis (ON). However, the full clinical spectrum of this newly described condition is unknown. We sought to describe non\u2010ON inflammatory ophthalmological presentations such as uveitis and optic perineuritis in the context of MOG antibody seropositivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using a live cell\u2010based assay analysed by flow cytometry, we identified seropositive patients referred for MOG antibody testing in Australasia between 2014 and 2017. We identified four MOG antibody\u2010positive patients with non\u2010ON inflammatory ophthalmological presentations and present their detailed clinical information in this case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three patients had uveitis either in association with, or remote from, ON. One patient had optic perineuritis and peripheral ulcerative keratitis. We describe the presentation, examination, investigation findings and clinical course of these four patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Recognition of these novel clinical associations may expand the clinical spectrum of MOG antibody\u2010associated presentations. An expedited diagnosis may guide the management of these complex patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.13932","type":"journal-article","created":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T19:48:11Z","timestamp":1550000891000},"page":"1137","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Uveitis and optic perineuritis in the context of myelin oligodendrocyte glycoprotein antibody seropositivity"],"prefix":"10.1111","volume":"26","author":[{"given":"S.","family":"Ramanathan","sequence":"first","affiliation":[{"name":"Brain Autoimmunity Group Kids Neuroscience Centre at Kids Research The Children's Hospital Westmead New South Wales"},{"name":"Sydney Medical School University of Sydney Sydney New South Wales"},{"name":"Department of Neurology Westmead Hospital Sydney New South Wales"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Fraser","sequence":"additional","affiliation":[{"name":"Save Sight Institute University of Sydney Sydney New South Wales"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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