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Fugl\u2010Meyer assessment and resting\u2010state functional magnetic resonance imaging were performed 1, 4 and 12\u00a0weeks after onset. Patients were further assigned to better and worse recovery subgroups according to the degree of motor recovery at the twelfth week after stroke. Voxel\u2010wise degree centrality (<jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content>)\u2013behavior correlation analysis was used to identify brain regions related to changes in motor function within 12\u00a0weeks after stroke.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significant correlation was found between <jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content> and Fugl\u2010Meyer scores within 12\u00a0weeks in the ipsilesional cerebellar crus I and crus <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> in patients with pontine infarction and in the ipsilesional middle temporal gyrus in patients with striato\u2010capsular infarction (all <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001, AlphaSim corrected). The mean <jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content> in these areas was higher both in the better and worse recovery subgroups at the fourth than at the first week (all <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05). In addition, the mean <jats:styled-content style=\"fixed-case\">DC<\/jats:styled-content> values in these areas were higher in patients with better recovery at the twelfth than at the first week (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.05), but such change was not found in patients with worse recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These results indicate that network changes in the ipsilesional cerebellum are correlated with motor recovery following pontine infarction. Motor recovery mechanisms may vary between pontine and striato\u2010capsular infarcts, according to lesion location.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.13974","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T11:27:20Z","timestamp":1556191640000},"page":"1266-1273","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Network change in the ipsilesional cerebellum is correlated with motor recovery following unilateral pontine infarction"],"prefix":"10.1111","volume":"26","author":[{"given":"G.","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Neurology and Stroke Center The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging State Key Laboratory of Oncology in Southern China Collaborative Innovation Center for Cancer Medicine Sun Yat\u2010Sen University Cancer Center Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Xing","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging State Key Laboratory of Oncology in Southern China Collaborative Innovation Center for Cancer Medicine Sun Yat\u2010Sen University Cancer Center Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1661-2442","authenticated-orcid":false,"given":"J.","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center The First Affiliated Hospital Sun Yat\u2010Sen University Guangzhou 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