{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T11:14:34Z","timestamp":1760267674446,"version":"3.40.5"},"reference-count":6,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T00:00:00Z","timestamp":1565568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>This study was conducted to evaluate whether post\u2010thymectomy rapid remission of ocular myasthenia gravis (<jats:styled-content style=\"fixed-case\">oMG<\/jats:styled-content>) is a prognostic indicator of good long\u2010term neurological outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty\u2010four <jats:styled-content style=\"fixed-case\">oMG<\/jats:styled-content> patients who underwent thymectomy at our institute were enrolled. The incidence of 5\u2010year complete stable remission (<jats:styled-content style=\"fixed-case\">CSR<\/jats:styled-content>) was compared between patients with rapid remission of <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> status (&lt;1\u00a0month after surgery) and those with non\u2010rapid remission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Kaplan\u2013Meier survival analysis indicated that the incidence of <jats:styled-content style=\"fixed-case\">CSR<\/jats:styled-content> was higher in <jats:styled-content style=\"fixed-case\">oMG<\/jats:styled-content> patients with rapid remission than in those without rapid remission (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001). Multivariate analysis showed that rapid remission (odds ratio 16.34, 95% confidence interval 3.58\u201374.60, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.001) is an independent prognostic factor for <jats:styled-content style=\"fixed-case\">CSR<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Postoperative rapid remission of <jats:styled-content style=\"fixed-case\">MG<\/jats:styled-content> status predicts a higher likelihood of complete remission in patients with <jats:styled-content style=\"fixed-case\">oMG<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14036","type":"journal-article","created":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T20:03:02Z","timestamp":1562961782000},"page":"1421-1423","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Rapid improvement of muscle weakness post\u2010thymectomy indicates good long\u2010term neurological outcome in patients with ocular myasthenia gravis"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9255-0549","authenticated-orcid":false,"given":"Y.","family":"Geng","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery West China Hospital of Sichuan University Chengdu China"},{"name":"Department of Lung Cancer Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Lung Cancer Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery West China Hospital of Sichuan University Chengdu China"},{"name":"Department of Lung Cancer Center West China Hospital of Sichuan University Chengdu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,8,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2008.07.012"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(02)00031-3"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.1.16"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-015-2325-8"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.12.3872"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.03.011"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.14036","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ene.14036","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.14036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T03:09:07Z","timestamp":1694228947000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.14036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,12]]},"references-count":6,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["10.1111\/ene.14036"],"URL":"https:\/\/doi.org\/10.1111\/ene.14036","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"type":"print","value":"1351-5101"},{"type":"electronic","value":"1468-1331"}],"subject":[],"published":{"date-parts":[[2019,8,12]]},"assertion":[{"value":"2018-12-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}