{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T23:23:08Z","timestamp":1784935388667,"version":"3.55.0"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T00:00:00Z","timestamp":1565568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Hypertrophy\/signal hyperintensity and\/or gadolinium enhancement of plexus structures on magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) are observed in two\u2010thirds of cases of typical chronic inflammatory demyelinating polyneuropathy (<jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content>). The objective of our study was to determine the additional benefit of plexus <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> in patients referred to tertiary centers with baseline clinical and electrophysiological characteristics suggestive of typical or atypical <jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 28 consecutive patients with initial suspicion of <jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content> were recruited in nine centers and followed for 2\u00a0years. Plexus <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> data from the initial assessment were reviewed centrally. Physicians blinded to the plexus <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> findings established the final diagnosis (<jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content> or neuropathy of another cause). The proportion of patients with abnormal <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> was analyzed in each group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Chronic inflammatory demyelinating polyneuropathy was confirmed in 14 patients (50%), as were sensorimotor <jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content> (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>6), chronic immune sensory polyradiculoneuropathy (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>2), motor <jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content> (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1) and multifocal acquired demyelinating sensory and motor neuropathy (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>5). A total of 37 plexus <jats:styled-content style=\"fixed-case\">MRIs<\/jats:styled-content> were performed (17 brachial, 19 lumbosacral and 8 in both localizations). <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> was abnormal in 5\/37 patients (14%), all of whom were subsequently diagnosed with <jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content> [5\/14(36%)], after an atypical baseline presentation. With plexus <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> results masked, non\u2010invasive procedures confirmed the diagnosis of <jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content> in all but one patient [1\/14 (7%)]. Knowledge of the abnormal <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> findings in the latter could have prevented nerve biopsy being performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Systematic plexus <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> in patients with initially suspected <jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content> provides little additional benefit in confirming the diagnosis of <jats:styled-content style=\"fixed-case\">CIDP<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14053","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T17:38:42Z","timestamp":1564162722000},"page":"181-187","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Prospective study of the additional benefit of plexus magnetic resonance imaging in the diagnosis of chronic 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