{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T02:22:24Z","timestamp":1792549344267,"version":"4.5.0"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,2,26]],"date-time":"2020-02-26T00:00:00Z","timestamp":1582675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001320","name":"Wolfson Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001320","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000274","name":"British Heart Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000274","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background and purpose<\/jats:title>\n                    <jats:p>Transient global amnesia (TGA) is characterized by a sudden onset of anterograde amnesia lasting up to 24\u00a0h. One major differential for TGA is transient epileptic amnesia, which typically lasts\u00a0&lt;\u00a01\u00a0h. However, TGA can also be short in duration and little is known about the time trends, characteristics and prognosis of TGA cases lasting\u00a0&lt;\u00a01\u00a0h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We compared the clinical features of TGA ascertained in two independent cohort studies in Oxfordshire, UK [Oxford cohort 1977\u20131987 versus Oxford Vascular Study (OXVASC) 2002\u20132018] to determine the time trends of clinical features of TGA. Results were validated in another independent contemporary TGA cohort in Italy [Northern Umbria TGA registry (NU) 2002\u20132018]. We compared the risk factors, clinical features and long\u2010term prognosis (major cardiovascular events, recurrent TGA and seizure\/epilepsy) of patients presenting with episodes lasting\u00a0&lt;\u00a01\u00a0h versus those lasting\u00a0\u2265\u00a01\u00a0h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 639 patients with TGA were included (114 Oxford cohort, 100 OXVASC, 425 NU). Compared with the original Oxford cohort, there were more cases with TGA lasting\u00a0&lt;\u00a01\u00a0h in OXVASC [32 (32.0%) vs. 9 (8.8%)] and NU (11.8% vs. 8.8% in Oxford cohort). In both OXVASC and NU, patient age, vascular risk factors and clinical features were largely similar between those with TGA lasting\u00a0&lt;\u00a01\u00a0h versus those lasting\u00a0\u2265\u00a01\u00a0h. Moreover, there was no difference in the long\u2010term risk of seizure\/epilepsy or major cardiovascular events between TGA lasting\u00a0&lt;\u00a01\u00a0h versus TGA lasting\u00a0\u2265\u00a01\u00a0h.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Short\u2010duration TGA episodes (&lt;1\u00a0h) were not uncommon and were more frequent than in earlier studies. The clinical features and long\u2010term prognosis of short\u2010duration TGA did not differ from more typical episodes lasting\u00a0\u2265\u00a01\u00a0h.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ene.14163","type":"journal-article","created":{"date-parts":[[2020,2,3]],"date-time":"2020-02-03T14:50:56Z","timestamp":1580741456000},"page":"887-893","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Time trends, frequency, characteristics and prognosis of short\u2010duration transient global amnesia"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8009-8543","authenticated-orcid":false,"given":"M.","family":"Romoli","sequence":"first","affiliation":[{"name":"Centre for Prevention of Stroke and Dementia Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK"},{"name":"Neurology Clinic University of Perugia \u2013 S. Maria della Misericordia Hospital Perugia"},{"name":"Neurology Unit Rimini \u2018Infermi\u2019 Hospital \u2013 AUSL Romagna Rimini"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Tuna","sequence":"additional","affiliation":[{"name":"Centre for Prevention of Stroke and Dementia Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3636-8355","authenticated-orcid":false,"given":"L.","family":"Li","sequence":"additional","affiliation":[{"name":"Centre for Prevention of Stroke and Dementia Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Paciaroni","sequence":"additional","affiliation":[{"name":"Stroke Unit University of Perugia \u2013 S. Maria della Misericordia Hospital of Perugia Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Giannandrea","sequence":"additional","affiliation":[{"name":"Neurology and Stroke Unit USL Umbria 1 Gubbio and Citt\u00e0 di Castello Hospital Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Tordo Caprioli","sequence":"additional","affiliation":[{"name":"Neurology Clinic University of Perugia \u2013 S. Maria della Misericordia Hospital Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Lotti","sequence":"additional","affiliation":[{"name":"Neurology Clinic University of Perugia \u2013 S. Maria della Misericordia Hospital Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Eusebi","sequence":"additional","affiliation":[{"name":"Neurology Clinic University of Perugia \u2013 S. Maria della Misericordia Hospital Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. G.","family":"Mosconi","sequence":"additional","affiliation":[{"name":"Stroke Unit University of Perugia \u2013 S. Maria della Misericordia Hospital of Perugia Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Pellizzaro Venti","sequence":"additional","affiliation":[{"name":"Stroke Unit University of Perugia \u2013 S. Maria della Misericordia Hospital of Perugia Perugia"},{"name":"Stroke Unit Addenbrooke's Hospital \u2013 Cambridge University Hospital Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Salvadori","sequence":"additional","affiliation":[{"name":"Neurology Clinic University of Perugia \u2013 S. Maria della Misericordia Hospital Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Gili","sequence":"additional","affiliation":[{"name":"Public Health Department University of Perugia Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Ricci","sequence":"additional","affiliation":[{"name":"Neurology and Stroke Unit USL Umbria 1 Gubbio and Citt\u00e0 di Castello Hospital Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Stracci","sequence":"additional","affiliation":[{"name":"Public Health Department University of Perugia Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Sarchielli","sequence":"additional","affiliation":[{"name":"Neurology Clinic University of Perugia \u2013 S. Maria della Misericordia Hospital Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Parnetti","sequence":"additional","affiliation":[{"name":"Neurology Clinic University of Perugia \u2013 S. Maria della Misericordia Hospital Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9739-9211","authenticated-orcid":false,"given":"P. M.","family":"Rothwell","sequence":"additional","affiliation":[{"name":"Centre for Prevention of Stroke and Dementia Nuffield Department of Clinical Neurosciences University of Oxford Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Calabresi","sequence":"additional","affiliation":[{"name":"Neurology Clinic University of Perugia \u2013 S. Maria della Misericordia Hospital Perugia"},{"name":"IRCCS \u2018Santa Lucia\u2019 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2014.12.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.10.834"},{"issue":"9","key":"e_1_2_7_4_1","first-page":"1","article-title":"Transient global amnesia","volume":"40","author":"Fisher CM","year":"1964","journal-title":"Acta Neurol Scand Suppl"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2012.264"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebcr.2014.03.008"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.64.4.435"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcs040"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.56.11.1184"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2015.07.020"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67702-1"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-016-1115-x"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2018.08.009"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fene.14163","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.14163","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ene.14163","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.14163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T14:34:38Z","timestamp":1693319678000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.14163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,26]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["10.1111\/ene.14163"],"URL":"https:\/\/doi.org\/10.1111\/ene.14163","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,26]]},"assertion":[{"value":"2019-09-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}