{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T01:29:20Z","timestamp":1768267760346,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T00:00:00Z","timestamp":1595376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Most recurrent cervical artery dissection (CeAD) events occur shortly after the acute first CeAD. This study compared the characteristics of recurrent and first CeAD events and searched for associations between subsequent events of an individual person.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Cervical artery dissection patients with a new CeAD event occurring during a 3\u20136\u00a0month follow\u2010up were retrospectively selected in seven specialized stroke centers. Clinical and vascular characteristics of the initial and the recurrent CeADs were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study sample included 76 patients. Recurrent CeADs were occlusive in one (1.3%) patient, caused cerebral ischaemia in 13 (17.1%) and were asymptomatic in 39 (51.3%) patients, compared to 29 (38.2%) occlusive, 42 (55.3%) ischaemic and no asymptomatic first CeAD events. In 52 (68.4%) patients, recurrent dissections affected both internal carotid arteries or both vertebral arteries, whilst 24 (31.6%) patients had subsequent dissections in both types of artery. Twelve (28.6%) of 42 patients with an ischaemic first dissection had ischaemic symptoms due to the recurrent CeADs, too. However, only one (1.3%) of 34 patients with a non\u2010ischaemic first CeAD suffered ischaemia upon recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Recurrent CeAD typically affects the same site of artery. It causes ischaemic events less often than the first CeAD. The risk that patients who presented with solely non\u2010ischaemic symptoms of a first CeAD will have ischaemic symptoms in the case of a recurrent CeAD seems very small.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14417","type":"journal-article","created":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T07:42:15Z","timestamp":1593416535000},"page":"2185-2190","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Recurrent versus first cervical artery dissection \u2013 a retrospective study of clinical and vascular characteristics"],"prefix":"10.1111","volume":"27","author":[{"given":"M.","family":"Kloss","sequence":"first","affiliation":[{"name":"Department of Neurology University of Heidelberg Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Kalashnikova","sequence":"additional","affiliation":[{"name":"Research Center of Neurology Russian Academy of Medical Sciences Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Dobrynina","sequence":"additional","affiliation":[{"name":"Research Center of Neurology Russian Academy of Medical Sciences Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Traenka","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center Basel University Hospital Basel Switzerland"},{"name":"Neurology and Neurorehabilitation University Department of Geriatric Medicine FELIX PLATTER University of Basel Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. T.","family":"Engelter","sequence":"additional","affiliation":[{"name":"Department of Neurology and Stroke Center Basel University Hospital Basel Switzerland"},{"name":"Neurology and Neurorehabilitation University Department of Geriatric Medicine FELIX PLATTER University of Basel Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. M.","family":"Metso","sequence":"additional","affiliation":[{"name":"Department of Neurology Helsinki University Central Hospital Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Tatlisumak","sequence":"additional","affiliation":[{"name":"Department of Neurology Helsinki University Central Hospital Helsinki Finland"},{"name":"Department of Clinical Neuroscience\/Neurology Institute of Neuroscience and Physiology Sahlgrenska Academy at University of Gothenburg Gothenburg Sweden"},{"name":"Department of Neurology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Urbanek","sequence":"additional","affiliation":[{"name":"Department of Neurology Klinikum Ludwigshafen Ludwigshafen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Grau","sequence":"additional","affiliation":[{"name":"Department of Neurology Klinikum Ludwigshafen Ludwigshafen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4967-8336","authenticated-orcid":false,"given":"L.","family":"Kellert","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Ludwig Maximilian University Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Brandt","sequence":"additional","affiliation":[{"name":"Suva\/Swiss National Accident Insurance Fund Lucerne Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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