{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:22:29Z","timestamp":1790871749993,"version":"4.1.0"},"reference-count":53,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T00:00:00Z","timestamp":1601856000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>The burden of cervical arterial atherosclerosis, which is an important risk factor of stroke, is huge in China. The visceral adiposity index (VAI) is a convenient index that is related to a series of metabolic abnormalities and a variety of diseases, including cerebrovascular diseases. This study aimed to explore the relationship between VAI and cervical arterial atherosclerosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study used the multistage stratified random cluster sampling method to acquire a representative sample of residents aged \u226540 in the general population of northeast China. All participants completed a detailed questionnaire and provided blood samples. Cervical vascular ultrasound was performed by experienced ultrasound doctors. VAI was calculated by a well\u2010established formula and analyzed by quartiles (Q1\u2013Q4).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 3688 people aged \u226540\u00a0years who underwent cervical arterial ultrasound were finally included, amongst whom 3.2% had increased intima\u2010media thickness (IMT), 48.6% had carotid plaque and 4.0% had cervical artery stenosis (CAS). After adjusting for several parameters, little statistical significance was found between VAI and increased IMT; compared with the VAI\u2010Q1 group, the VAI\u2010Q2, VAI\u2010Q3 and VAI\u2010Q4 groups were more likely to have CAS [odds ratio (OR) 2.01, 95% confidence interval (CI) 1.17\u20133.43; OR 1.82, 95% CI 1.05\u20133.15; OR 1.79, 95% CI 1.03\u20133.12] and the VAI\u2010Q3 and VAI\u2010Q4 groups were at greater risk of carotid plaque (OR 1.30, 95% CI 1.05\u20131.62; OR 1.34, 95% CI 1.07\u20131.67).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The VAI was related to carotid plaque and CAS in the general population that is older than 40\u00a0years.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14513","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T16:03:54Z","timestamp":1601049834000},"page":"161-171","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Visceral adiposity index and cervical arterial atherosclerosis in northeast China: a population based cross\u2010sectional survey"],"prefix":"10.1111","volume":"28","author":[{"given":"Y.","family":"Yu","sequence":"first","affiliation":[{"name":"Stroke Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Neuroscience Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Clinical Trial and Research Center for Stroke Department of Neurology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.\u2010L.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Stroke Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Neuroscience Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Clinical Trial and Research Center for Stroke Department of Neurology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.\u2010L.","family":"Yan","sequence":"additional","affiliation":[{"name":"Stroke Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Neuroscience Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Clinical Trial and Research Center for Stroke Department of Neurology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Stroke Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Neuroscience Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Clinical Trial and Research Center for Stroke Department of Neurology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.\u2010N.","family":"Guo","sequence":"additional","affiliation":[{"name":"Stroke Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Neuroscience Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Clinical Trial and Research Center for Stroke Department of Neurology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9729-8522","authenticated-orcid":false,"given":"Y.","family":"Yang","sequence":"additional","affiliation":[{"name":"Stroke Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Neuroscience Center Department of Neurology First Hospital of Jilin University Changchun China"},{"name":"Clinical Trial and Research Center for Stroke Department of Neurology First Hospital of Jilin University Changchun China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32203-7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.118.008701"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2018.07.020"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn387"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.06.032"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.01.003"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/2012.jama.11132"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2010.12.023"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000001824"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-1825"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000446121"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11739-018-1836-8"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3052"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2017.06.015"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.112.035758"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-015758"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2013.12.017"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2017.08.033"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.47274"},{"key":"e_1_2_8_21_1","first-page":"220","article-title":"Indicators of abdominal adiposity and carotid intima\u2010media thickness: results from the longitudinal study of adult health (ELSA\u2010Brazil)","volume":"112","author":"Eickemberg M","year":"2019","journal-title":"Arq Bras Cardiol"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-014-0139-2"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.11.045"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.107.484113"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.847"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000018650.58984.75"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.09.024"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00630-3"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-017-0453-2"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.14336\/AD.2018.0602"},{"key":"e_1_2_8_31_1","first-page":"599","article-title":"Chinese stroke vascular ultrasound examination guidelines","volume":"12","author":"Hua YHP","year":"2015","journal-title":"Chin J Med Ultrasound"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2292030516"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.2624"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2010.12.003"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/730827"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2013.04.006"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-014-0471-z"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjdrc-2019-000911"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.21540"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.33399"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2015.06.007"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.18663"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2009.81"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2009.01.046"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-018-4095-0"},{"key":"e_1_2_8_46_1","first-page":"S62","article-title":"Novel mathematic indexes to identify subclinical atherosclerosis in different obesity phenotypes of perimenopausal\/menopausal women","volume":"99","author":"Tongdee P","year":"2016","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_8_47_1","first-page":"S30","article-title":"Application of visceral adiposity index and anthropometry to identify preclinical atherosclerosis in menopausal status women","volume":"99","author":"Tongdee P","year":"2016","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-2775"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2014.11.031"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI21625"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2008.00102.x"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20071063"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2007.09.019"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.03.023"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.14513","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ene.14513","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.14513","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T06:10:57Z","timestamp":1693289457000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.14513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,5]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1111\/ene.14513"],"URL":"https:\/\/doi.org\/10.1111\/ene.14513","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,5]]},"assertion":[{"value":"2020-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}