{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T02:51:09Z","timestamp":1778640669470,"version":"3.51.4"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,10,10]],"date-time":"2020-10-10T00:00:00Z","timestamp":1602288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Dysphagia is common in acute stroke and leads to worse overall outcome. Transesophageal echocardiography (TEE) is used in the diagnostic evaluation of stroke with regard to its etiology and is a known cause of postoperative dysphagia in cardiac surgery. The prevalence of dysphagia in acute stroke patients undergoing TEE remains unknown. The aim of the Transesophageal Echocardiography \u2013 Dysphagia Risk in Acute Stroke (TEDRAS) study was to assess the influence of TEE on swallowing among patients who have experienced acute stroke.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The TEDRAS study was a prospective, blind, randomized, controlled trial that included two groups of patients with acute stroke. Simple unrestricted randomization was performed, and examiners were blinded to each other's results. Swallowing was tested using flexible endoscopic evaluation of swallowing (FEES) at three different time points in the intervention group (24\u00a0h before, immediately after and 24\u00a0h after TEE) and in the control group (FEES on three consecutive days and TEE earliest after the third FEES). Validated scales were used to assess dysphagia severity for all time points as primary outcome measures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 34 patients were randomized: 19 to the intervention group and 15 to the control group. The key findings of the repeated\u2010measures between\u2010group comparisons were significant increases in the intervention group for the following dysphagia measures: (1) secretion severity score (immediately after TEE: <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001; 24\u00a0h after TEE: <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and (2) Penetration\u2010Aspiration Scale score for saliva (immediately after TEE: <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001; 24\u00a0h after TEE: <jats:italic>P<\/jats:italic>\u00a0=\u00a00.007), for small (immediately after TEE: <jats:italic>P<\/jats:italic>\u00a0=\u00a00.009) and large liquid boli (immediately after TEE: <jats:italic>P<\/jats:italic>\u00a0=\u00a00.009; 24\u00a0h after TEE: <jats:italic>P<\/jats:italic>\u00a0=\u00a00.025).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The results indicate a negative influence of TEE on swallowing in acute stroke patients for at least 24 hours.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14516","type":"journal-article","created":{"date-parts":[[2020,10,11]],"date-time":"2020-10-11T04:11:13Z","timestamp":1602389473000},"page":"172-181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Transesophageal Echocardiography \u2013 Dysphagia Risk in Acute Stroke (TEDRAS): a prospective, blind, randomized and controlled clinical trial"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4384-0400","authenticated-orcid":false,"given":"S.","family":"Hamzic","sequence":"first","affiliation":[{"name":"Department of Neurology University Hospital Giessen and Marburg GmbH Justus\u2010Liebig\u2010University Giessen Germany"},{"name":"Heart and Brain Research Group Heart\u2010, Lung\u2010, Vascular\u2010 and Rheumatic Centre Bad Nauheim Kerckhoff Clinic GmbH Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1738-2773","authenticated-orcid":false,"given":"T.","family":"Braun","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Giessen and Marburg GmbH Justus\u2010Liebig\u2010University Giessen Germany"},{"name":"Heart and Brain Research Group Heart\u2010, Lung\u2010, Vascular\u2010 and Rheumatic Centre Bad Nauheim Kerckhoff Clinic GmbH Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Butz","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Giessen and Marburg GmbH Justus\u2010Liebig\u2010University Giessen Germany"},{"name":"Heart and Brain Research Group Heart\u2010, Lung\u2010, Vascular\u2010 and Rheumatic Centre Bad Nauheim Kerckhoff Clinic GmbH Bad Nauheim 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