{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T19:34:00Z","timestamp":1769110440765,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>According to current guidelines, patients with aneurysmal subarachnoid haemorrhage (aSAH) are mostly managed in intensive care units (ICUs) regardless of baseline severity. We aimed to assess the prognostic and economic implications of initial admission of patients with low\u2010grade aSAH into a stroke unit (SU) compared to initial ICU admission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed prospectively registered data from consecutive aSAH patients with a World Federation of Neurosurgery Societies grade &lt;3, admitted to our Comprehensive Stroke Centre between April 2013 and September 2018. Clinical and radiological baseline traits, in\u2010hospital complications, length of stay (LOS) and poor outcome at 90\u00a0days (modified Rankin Scale score &gt;\u00a02) were compared between the ICU and SU groups in the whole population and in a propensity\u2010score\u2010matched cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 131 patients, 74 (56%) were initially admitted to the ICU and 57 (44%) to the SU. In\u2010hospital complication rates were similar in the ICU and SU groups and included rebleeding (10% vs. 7%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.757), angiographic vasospasm (61% vs. 60%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.893), delayed cerebral ischaemia (12% vs. 12%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.984), pneumonia (6% vs. 4%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.697) and death (10% vs. 5%; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.512). LOS did not differ between groups (median [interquartile range] 22 [16\u201330] vs. 19 [14\u201326] days; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.160). In adjusted multivariate models, the location of initial admission was not associated with long\u2010term poor outcome either in the whole population (odds ratio [OR]\u00a01.16, 95% confidence interval [CI] 0.32\u20134.19; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.825) or in the matched cohort (OR 0.98, 95% CI 0.24\u20134.06; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.974).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A dedicated SU, with care from a multidisciplinary team, might be an optimal alternative to ICU for initial admission of patients with low\u2010risk aSAH.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14548","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T01:06:49Z","timestamp":1600823209000},"page":"500-508","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Stroke units could be a valid alternative to intensive care units for patients with low\u2010grade aneurysmal subarachnoid haemorrhage"],"prefix":"10.1111","volume":"28","author":[{"given":"L.","family":"Llull","sequence":"first","affiliation":[{"name":"Comprehensive Stroke Centre Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"May\u00e0","sequence":"additional","affiliation":[{"name":"Comprehensive Stroke Centre Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Torn\u00e9","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Mellado\u2010Artigas","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ren\u00fa","sequence":"additional","affiliation":[{"name":"Comprehensive Stroke Centre Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"L\u00f3pez\u2010Rueda","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Laredo","sequence":"additional","affiliation":[{"name":"Comprehensive Stroke Centre Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Culebras","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Ferrando","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Hospital Cl\u00ednic Barcelona University of Barcelona and August Pi I Sunyer Biomedical Research Institute (IDIBAPS) Barcelona 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