{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T11:27:40Z","timestamp":1788866860348,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,1,21]],"date-time":"2021-01-21T00:00:00Z","timestamp":1611187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Sleep disturbance and cognitive impairment are common and related in the elderly population worldwide. The aim of the present study was to explore the association between sleep disturbance and motoric cognitive risk (MCR) syndrome, which is characterized by subjective cognitive complaints and objective slow gait in older individuals without dementia or any mobility disability in the community\u2010dwelling elderly Chinese population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We recruited 940 participants aged\u00a0\u226565\u00a0years from November 2016 to March 2017 in the Ningbo Community Study on Aging (NCSA). Self\u2010reported sleep duration and sleep\u2010quality variables, comprehensive geriatric evaluation, as well as indicators for diagnosing MCR syndrome were evaluated in this cross\u2010sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Multiple logistic regression analysis showed that a 1\u2010SD increase in night (1.1\u00a0h) and 24\u2010h sleep duration (1.3\u00a0h) was associated, respectively, with a 21% (95% confidence interval [CI], 1%\u201347%; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.04) and 30% (95% CI, 3%\u201364%; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.03) higher odds of having MCR syndrome. Considering sleep duration as a categorical variable, longer night\u2010sleep duration (&gt;8.5\u00a0h) was associated with MCR syndrome (OR, 2.03; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.02) compared to shorter night\u2010sleep duration (&lt;8\u00a0h). For sleep\u2010quality factors, increasing frequency of trouble falling asleep, waking early or easily, nightmares, and taking sleep drugs were significantly associated with MCR syndrome after adjusting for potential covariables (all <jats:italic>p<\/jats:italic> for trend\u00a0&lt;\u00a00.05), but not for self\u2010perceived sleep quality (<jats:italic>p<\/jats:italic> for trend\u00a0=\u00a00.10).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Long sleep duration, poor sleep quality, and taking sleep drugs were associated with higher odds of having MCR syndrome in the community\u2010dwelling elderly Chinese population. Further research is needed to explore the underlying mechanisms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14681","type":"journal-article","created":{"date-parts":[[2020,12,15]],"date-time":"2020-12-15T04:05:10Z","timestamp":1608005110000},"page":"1470-1478","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Association between sleep disturbance with motoric cognitive risk syndrome in Chinese older adults"],"prefix":"10.1111","volume":"28","author":[{"given":"Weifang","family":"Zeng","sequence":"first","affiliation":[{"name":"Department of Cardiology HwaMei Hospital, University of the Chinese Academy of Sciences Ningbo Cardiovascular Center Ningbo Zhejiang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1137-8055","authenticated-orcid":false,"given":"Lu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology HwaMei Hospital, 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