{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T15:28:27Z","timestamp":1790263707836,"version":"4.1.0"},"reference-count":14,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,6,20]],"date-time":"2021-06-20T00:00:00Z","timestamp":1624147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008952","name":"Agence Nationale pour le D\u00e9veloppement de la Recherche Universitaire","doi-asserted-by":"publisher","award":["ANR\u201010\u2010IAIHU\u201006"],"award-info":[{"award-number":["ANR\u201010\u2010IAIHU\u201006"]}],"id":[{"id":"10.13039\/501100008952","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Psychogenic non\u2010epileptic seizure\u2010status (PNES\u2010status), defined by psychogenic non\u2010epileptic seizures (PNES) over 30\u00a0min, are often misdiagnosed as status epilepticus. We aimed to describe the features of patients who experienced PNES\u2010status, admitted to an intensive care unit (ICU).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We screened the patients hospitalized in our epilepsy unit during a 4\u2010year period, with a diagnosis of PNES\u2010status and ICU admission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 171 patients with PNES, we identified 25 patients (15%) who presented 39 episodes of PNES\u2010status leading to ICU admission. Some 76% of the patients were women. The median age at the time of the PNES\u2010status episode was 35\u00a0years. Half (48%) alleged a history of epilepsy, but epilepsy was confirmed in only 12%. A history of psychiatric disease was found in 68%. PNES were present in 85% of patients before PNES\u2010status, and semiology of PNES and PNES\u2010status was similar for 79% of the patients, including hyperkinetic movements in 95% of the episodes and suspected loss of consciousness in 87%. Benzodiazepines were administrated in 77% of the episodes, antiepileptic drugs in 87%, and antibiotherapy for a ICU\u2010related infection in 15% of the episodes. Oral intubation was performed in 41% of the episodes. Blood tests showed normal levels of creatine phosphokinase and leucocytes in 90% and 95% of the episodes, respectively. No epileptic activity was found during per\u2010event electroencephalography but interictal epileptic activity was found in 10% of the episodes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hyperkinetic PNES\u2010status should always be considered as a differential diagnosis of status epilepticus, with a high risk of iatrogenic consequences.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14941","type":"journal-article","created":{"date-parts":[[2021,5,25]],"date-time":"2021-05-25T15:47:57Z","timestamp":1621957677000},"page":"2775-2779","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Psychogenic non\u2010epileptic seizure\u2010status in patients admitted to the intensive care unit"],"prefix":"10.1111","volume":"28","author":[{"given":"Nicolas","family":"Mezouar","sequence":"first","affiliation":[{"name":"AP\u2010HP Epilepsy Unit and Neurophysiology Department Piti\u00e9\u2010Salp\u00eatri\u00e8re Hospital Paris France"},{"name":"Sorbonne Universit\u00e9 Paris France"},{"name":"Reference Center for Rare Epilepsies Piti\u00e9\u2010Salp\u00eatri\u00e8re Hospital Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Demeret","sequence":"additional","affiliation":[{"name":"AP\u2010HP Neuro\u2010Intensive Care Unit Piti\u00e9\u2010Salp\u00eatri\u00e8re Hospital Paris France"},{"name":"Paris Brain Institute ICM Inserm U 1127 CNRS UMR 7225 Sorbonne Universit\u00e9 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Yves","family":"Rotge","sequence":"additional","affiliation":[{"name":"Paris Brain Institute ICM Inserm U 1127 CNRS UMR 7225 Sorbonne Universit\u00e9 Paris France"},{"name":"AP\u2010HP Psychiatry Department Piti\u00e9\u2010Salp\u00eatri\u00e8re Hospital Paris 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