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We aimed to define factors predicting the severity of COVID\u201019 in MG patients and risk of MG exacerbation during COVID\u201019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We evaluated clinical features and outcomes after COVID\u201019 in 93 MG patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010five patients (38%) had severe pneumonia and we recorded 10 deaths (11%) due to COVID\u201019. Higher forced vital capacity (FVC) values tested before COVID\u201019 were shown to be protective against severe infection (95% CI 0.934\u20130.98) as well as good control of MG measured by the quantified myasthenia gravis score (95% CI 1.047\u20131.232). Long\u2010term chronic corticosteroid treatment worsened the course of COVID\u201019 in MG patients (95% CI 1.784\u2013111.43) and this impact was positively associated with dosage (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.005). Treatment using azathioprine (95% CI 0.448\u20132.935), mycophenolate mofetil (95% CI 0.91\u201312.515) and ciclosporin (95% CI 0.029\u20132.212) did not influence the course of COVID\u201019. MG patients treated with rituximab had a high risk of death caused by COVID\u201019 (95% CI 3.216\u2013383.971). Exacerbation of MG during infection was relatively rare (15%) and was not caused by remdesivir, convalescent plasma or favipiravir (95% CI 0.885\u201310.87).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>As the most important predictors of severe COVID\u201019 in MG patients we identified unsatisfied condition of MG with lower FVC, previous long\u2010term corticosteroid treatment especially in higher doses, older age, the presence of cancer, and recent rituximab treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.14951","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T08:20:00Z","timestamp":1622708400000},"page":"3418-3425","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Predictive factors for a severe course of COVID\u201019 infection in myasthenia gravis patients with an overall impact on myasthenic outcome status and 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