{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T14:12:59Z","timestamp":1783433579265,"version":"3.54.6"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T00:00:00Z","timestamp":1638576000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>To explore the prevalence, risk factors, time correlation, characteristics and clinical outcome of dural arteriovenous fistulas (dAVFs) in a cerebral venous thrombosis (CVT) population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included patients from the International CVT Consortium registries. Diagnosis of dAVF was confirmed centrally. We assessed the prevalence and risk factors for dAVF among consecutive CVT patients and investigated its impact on clinical outcome using logistic regression analysis. We defined poor outcome as modified Rankin Scale score 3\u20136 at last follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>dAVF was confirmed in 29\/1218 (2.4%) consecutive CVT patients. The median (interquartile range [IQR]) follow\u2010up time was 8\u00a0(5\u201323) months. Patients with dAVF were older (median [IQR] 53\u00a0[44\u201361] vs. 41\u00a0[29\u201353] years; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), more frequently male (69% vs. 33%; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), more often had chronic clinical CVT onset (&gt;30 days: 39% vs. 7%; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) and sigmoid sinus thrombosis (86% vs. 51%; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001), and less frequently had parenchymal lesions (31% vs. 55%; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.013) at baseline imaging. Clinical outcome at last follow\u2010up did not differ between patients with and without dAVF. Additionally, five patients were confirmed with dAVF from non\u2010consecutive CVT cohorts. Among all patients with CVT and dAVF, 17\/34 (50%) had multiple fistulas and 23\/34 (68%) had cortical venous drainage. Of 34 patients with dAVF with 36 separate CVT events, 3\/36 fistulas (8%) were diagnosed prior to, 20\/36 (56%) simultaneously and 13\/36 after (36%, median 115 [IQR 38\u2013337] days) diagnosis of CVT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dural arteriovenous fistulas occur in at least 2% of CVT patients and are associated with chronic CVT onset, older age and male sex. Most CVT\u2010related dAVFs are detected simultaneously or subsequently to diagnosis of CVT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.15192","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T09:52:14Z","timestamp":1637661134000},"page":"761-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Dural arteriovenous fistulas in cerebral venous thrombosis"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7628-5044","authenticated-orcid":false,"given":"Erik","family":"Lindgren","sequence":"first","affiliation":[{"name":"Department of Clinical Neuroscience Institute of Neuroscience and Physiology Sahlgrenska Academy at University of Gothenburg Gothenburg Sweden"},{"name":"Department of Neurology Sahlgrenska University Hospital Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandros","family":"Rentzos","sequence":"additional","affiliation":[{"name":"Diagnostic and Interventional Neuroradiology Sahlgrenska University Hospital Gothenburg V\u00e4stra G\u00f6taland County Sweden"},{"name":"Department of Radiology Institute of Clinical Sciences Sahlgrenska Academy at University of Gothenburg Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sini","family":"Hiltunen","sequence":"additional","affiliation":[{"name":"Department of Neurology Helsinki University Hospital and University of Helsinki Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiola","family":"Serrano","sequence":"additional","affiliation":[{"name":"National Institute of Neurology Neurosurgery Manuel Velasco Suarez Mexico\u2010City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3594-2159","authenticated-orcid":false,"given":"Mirjam R.","family":"Heldner","sequence":"additional","affiliation":[{"name":"Department of Neurology Inselspital Bern University Hospital and University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna M.","family":"Zuurbier","sequence":"additional","affiliation":[{"name":"Department of Neurology Amsterdam University Medical Centers, AMC Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne M.","family":"Silvis","sequence":"additional","affiliation":[{"name":"Department of Neurology Amsterdam University Medical Centers, AMC Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Mansour","sequence":"additional","affiliation":[{"name":"Department of Neurology Sina Hospital Hamadan University of Medical Science Hamadan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Allingham","sequence":"additional","affiliation":[{"name":"The Balfour Hospital National Health Service Orkney Kirkwall Orkney UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin N. 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