{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T03:37:46Z","timestamp":1768621066475,"version":"3.49.0"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,4,9]],"date-time":"2023-04-09T00:00:00Z","timestamp":1680998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2023,7]]},"abstract":"Abstract<\/jats:title>Background and purpose<\/jats:title>There is a need to improve the diagnostic process of patients suspected of papilledema. In patients with known or suspected idiopathic intracranial hypertension a fundus imaging and perimetric visual field assessment system (COMPASS) performed at a headache center was validated in comparison to an assessment (Topcon plus OCTOPUS) at a neuroophthalmological clinic.<\/jats:p><\/jats:sec>Methods<\/jats:title>For intermethod assessment, blinded fundus images and perimetry from COMPASS versus Topcon plus OCTOPUS were assessed by a neuroophthalmologist. For interrater assessment, fundus images and perimetry obtained by the COMPASS system were assessed by an untrained medical doctor, a trained neurologist and a trained medical student and compared to the neuroophthalmologist's assessments.<\/jats:p><\/jats:sec>Results<\/jats:title>For the intermethod variation of the presence of papilledema on fundus images, a kappa value of 0.60, sensitivity of 87% and specificity of 73% were found. The interrater variation of the presence of papilledema on fundus images showed kappa values ranging from 0.43 to 0.74, sensitivity values ranging from 70% to 96% and specificity values ranging from 46% to 93% when comparing the assessments made by the headache center staff with neuroophthalmologist's assessments. The COMPASS showed a 59% sensitivity and moderate agreement in detecting visual field defects compared with OCTOPUS. The visual field assessment showed only slight to fair agreement from 0.19 to 0.31 between assessments made by the headache center staff and the neuroophthalmologist.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The COMPASS system can be used with reasonable sensitivity in the assessment of papilledema in patients suspected of idiopathic intracranial hypertension at a tertiary headache center.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.15802","type":"journal-article","created":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T14:48:38Z","timestamp":1679928518000},"page":"1973-1982","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Fundus imaging and perimetry in patients with idiopathic intracranial hypertension\u2014an intermethod and interrater validity study"],"prefix":"10.1111","volume":"30","author":[{"given":"Zainab","family":"Rissan","sequence":"first","affiliation":[{"name":"Danish Headache Center Rigshospitalet Glostrup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadja Skadk\u00e6r","family":"Hansen","sequence":"additional","affiliation":[{"name":"Danish Headache Center Rigshospitalet Glostrup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3634-7287","authenticated-orcid":false,"given":"Louise Ninett","family":"Carlsen","sequence":"additional","affiliation":[{"name":"Danish Headache Center Rigshospitalet Glostrup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5730-0712","authenticated-orcid":false,"given":"Johanne Juhl","family":"Korsb\u00e6k","sequence":"additional","affiliation":[{"name":"Danish Headache Center Rigshospitalet Glostrup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rigmor H\u00f8jland","family":"Jensen","sequence":"additional","affiliation":[{"name":"Danish Headache Center Rigshospitalet Glostrup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Hamann","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Rigshospitalet University of Copenhagen Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6262-2986","authenticated-orcid":false,"given":"Henrik Winther","family":"Schytz","sequence":"additional","affiliation":[{"name":"Danish Headache Center Rigshospitalet Glostrup Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2017-317440"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1553-2712.2011.01147.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000115"},{"key":"e_1_2_8_5_1","volume-title":"Approach to Optic Disc Edema by Dr. Kathleen Digre","author":"Digre K","year":"2018"},{"key":"e_1_2_8_6_1","article-title":"Approach to the patient with bilateral optic disc swelling","author":"Golnik K","year":"2017","journal-title":"Cybersight"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.45.1.13"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13664"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.11613\/BM.2012.031"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1120672120945052"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000821"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.08.010"},{"key":"e_1_2_8_13_1","article-title":"Idiopathic intracranial hypertension: papilledema and neuro\u2010ophthalmology referral patterns","author":"Paul G","year":"2016","journal-title":"Pract Neurol"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000001660"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002318"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2013.01.010"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-18626"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2014.133"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-199906000-00004"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1989.01070010083032"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000000419"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.15802","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T20:48:52Z","timestamp":1692478132000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.15802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,9]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7]]}},"alternative-id":["10.1111\/ene.15802"],"URL":"https:\/\/doi.org\/10.1111\/ene.15802","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,9]]},"assertion":[{"value":"2023-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}