{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T05:56:38Z","timestamp":1777960598537,"version":"3.51.4"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:00:00Z","timestamp":1684800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Post\u2010stroke dysphagia affects outcome. In acute stroke patients, the aim was to evaluate clinical, cognitive and neuroimaging features associated with dysphagia and develop a predictive score for dysphagia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Ischaemic stroke patients underwent clinical, cognitive and pre\u2010morbid function evaluations. Dysphagia was retrospectively scored on admission and discharge with the Functional Oral Intake Scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all, 228 patients (mean age 75.8\u2009years; 52% males) were included. On admission, 126 (55%) were dysphagic (Functional Oral Intake Scale \u22646). Age (odds ratio [OR] 1.03, 95% confidence interval [CI] 1.00\u20131.05), pre\u2010event modified Rankin scale (mRS) score (OR 1.41, 95% CI 1.09\u20131.84), National Institutes of Health Stroke Scale (NIHSS) score (OR 1.79, 95% CI 1.49\u20132.14), frontal operculum lesion (OR 8.53, 95% CI 3.82\u201319.06) and Oxfordshire total anterior circulation infarct (TACI) (OR 1.47, 95% CI 1.05\u20132.04) were independently associated with dysphagia at admission. Education (OR 0.91, 95% CI 0.85\u20130.98) had a protective role. At discharge, 82 patients (36%) were dysphagic. Pre\u2010event mRS (OR 1.28, 95% CI 1.04\u20131.56), admission NIHSS (OR 1.88, 95% CI 1.56\u20132.26), frontal operculum involvement (OR 15.53, 95% CI 7.44\u201332.43) and Oxfordshire classification TACI (OR 3.82, 95% CI 1.95\u20137.50) were independently associated with dysphagia at discharge. Education (OR 0.89, 95% CI 0.83\u20130.96) and thrombolysis (OR 0.77, 95% CI 0.23\u20130.95) had a protective role. The 6\u2010point \u201cNOTTEM\u201d (NIHSS, opercular lesion, TACI, thrombolysis, education, mRS) score predicted dysphagia at discharge with good accuracy. Cognitive scores had no role in dysphagia risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dysphagia predictors were defined and a score was developed to evaluate dysphagia risk during stroke unit stay. In this setting, cognitive impairment is not a predictor of dysphagia. Early dysphagia assessment may help in planning future rehabilitative and nutrition strategies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.15846","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T21:25:13Z","timestamp":1683753913000},"page":"2324-2337","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Early predictors of dysphagia in ischaemic stroke patients"],"prefix":"10.1111","volume":"30","author":[{"given":"Daniele","family":"Mattavelli","sequence":"first","affiliation":[{"name":"Neurology and Stroke Unit Luigi Sacco Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Mele","sequence":"additional","affiliation":[{"name":"Neurology and Stroke Unit Luigi Sacco Hospital  Milan 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