{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:47:39Z","timestamp":1792176459442,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T00:00:00Z","timestamp":1689638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Euro J of Neurology"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>Patients with idiopathic trigeminal neuralgia (TN) with absent arterial contact or venous contact only and classic TN with morphological changes of the trigeminal nerve secondary to venous compression are not routinely recommended microvascular decompression at our institution. In patients with these anatomical subtypes of TN, limited data exists describing the outcomes of percutaneous glycerol rhizolysis (PGR) of the trigeminal ganglion (TG).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective single\u2010center cohort study and analyzed outcomes and complications after PGR of the TG. Clinical outcome after PGR of the TG was assessed via the Barrow Neurological Institute (BNI) Pain Scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010five patients underwent a total of 66 PGRs of the TG. At short\u2010term follow\u2010up, 58 procedures (87.9%) resulted in a BNI score of I (i.e., freedom from pain without medication). At a median follow\u2010up of 3.07\u2009years, 18 procedures (27.3%) resulted in a BNI score of I, 12 procedures (18.1%) resulted in BNI score of IIIa, and 36 procedures (54.5%) resulted in a BNI score of IIIb\u2010V. The median length of freedom from pain without medication was 1.5\u2009years. Eighteen procedures (27.3%) caused hypesthesia and two (3.0%) caused paresthesias. There were no serious complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with these anatomical subtypes of TN there was a high rate of short\u2010term pain relief for the first 1\u20132\u2009years and thereafter a large proportion of patients experienced pain relapse. In this patient group, PGR of the TG represents a safe procedure that is efficacious in the short term.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ene.15977","type":"journal-article","created":{"date-parts":[[2023,7,9]],"date-time":"2023-07-09T21:29:00Z","timestamp":1688938140000},"page":"3307-3313","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Percutaneous glycerol rhizolysis of the trigeminal ganglion for the treatment of idiopathic and classic trigeminal neuralgia: Outcomes and complications"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8083-7764","authenticated-orcid":false,"given":"Raviteja","family":"Bethamcharla","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery Columbia University Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussam","family":"Abou\u2010Al\u2010Shaar","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery University of Pittsburgh Medical Center  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stine","family":"Maarbjerg","sequence":"additional","affiliation":[{"name":"Danish Headache Centre, Department of Neurology Glostrup Hospital, University of Copenhagen  Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue\u2010Fang","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery University of Pittsburgh Medical Center  Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline N.","family":"Gacka","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery Columbia University Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Raymond F.","family":"Sekula","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery Columbia University Medical Center  New York New York USA"},{"name":"Department of Neurological Surgery Columbia University Vagelos College of Physicians and Surgeons  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,18]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"International Headache Society.International Classification of Headache Disorders\u20103. Accessed January 18th 2023.https:\/\/ichd\u20103.org\/13\u2010painful\u2010cranial\u2010neuropathies\u2010and\u2010other\u2010facial\u2010pains\/13\u20101\u2010trigeminal\u2010neuralgia\/"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199604253341701"},{"key":"e_1_2_9_4_1","first-page":"1","article-title":"A novel scoring system as a preoperative predictor for pain\u2010free survival after microsurgery for trigeminal neuralgia","volume":"25","author":"Hardaway FA","year":"2019","journal-title":"J Neurosurg"},{"key":"e_1_2_9_5_1","first-page":"1","article-title":"Significance of degree of neurovascular compression in surgery for trigeminal neuralgia","volume":"14","author":"Hughes MA","year":"2019","journal-title":"J Neurosurg"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyz376"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu349"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuchi.2009.12.004"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.2.JNS131288"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-022-01520-x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.14.14156"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2015.10.008"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2005.18.5.8"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1958.10501452"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.72.6.0851"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01405534"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-019-0973-4"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000853"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina47070055"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-015-0548-y"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000114867.98896.F0"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000058546.16985.11"}],"container-title":["European Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ene.15977","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T09:47:57Z","timestamp":1694080077000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ene.15977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,18]]},"references-count":21,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1111\/ene.15977"],"URL":"https:\/\/doi.org\/10.1111\/ene.15977","archive":["Portico"],"relation":{},"ISSN":["1351-5101","1468-1331"],"issn-type":[{"value":"1351-5101","type":"print"},{"value":"1468-1331","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,18]]},"assertion":[{"value":"2023-01-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}